Scaling the Oxygen Uptake Efficiency Slope for Body Size in Cystic Fibrosis

Purpose: The aim of this study was to describe the relationship between body size and oxygen uptake efficiency slope (OUES) in pediatric patients with cystic fibrosis (CF) and healthy controls (CON), to identify appropriate scaling procedures to adjust the influence of body size upon OUES. Methods: The OUES was derived using maximal and submaximal points from cardiopulmonary exercise testing in 72 children (36 CF and 36 CON). OUES was subsequently scaled for stature, body mass (BM), and body surface area (BSA) using ratio-standard (Y/X) and allometric (Y/Xb) methods. Pearson's correlation coefficients were used to determine the relationship between body size and OUES. Results: When scaled using the ratio-standard method, OUES had a significant positive relationship with stature (r = 0.54, P 0.05) correlations for the whole group were found between OUES and allometrically scaled BM (CF r = −0.25, CON, r = 0.15) and BSA (CF r = −0.27, CON r = 0.13). Conclusions: Only allometric scaling of either BM or BSA, and not ratio-standard scaling, successfully eliminates the influence of body size upon OUES. Therefore, this enables a more direct comparison of the OUES between patients with CF and healthy controls.

from Sports Medicine via xlomafota13 on Inoreader http://ift.tt/2xPTNAe
via IFTTT