Comparative Evaluation of Strontium Chloride Desensitizer and Novel Proarginin Desensitizer on Dentinal Tubule Occlusion-A Scanning Electron Microscopic Study

2017-01-03T03-00-06Z
Source: National Journal of Integrated Research in Medicine
Mayur Parmar*, Surabhi Joshi**, Mira Thakkar***, Chintan Joshi****, Pratik Rupakar*****, Hima Desai*****.
Background: Dentinal hypersensitivity is the commonest dental problem. For this,the products that occlude the dentinal tubules are most widely accepted. Objective: The objective of the present study was to compare the effects of a well-established desensitizing dentifrice containing 2% strontium chloride with a new product 8% arginine on the dentinal tubules, following repeated brushing strokes on a dentine disc model. Methods: For the study, freshly extracted premolars were sectioned at the level of CEJ. The prepared dentin discs were cleaned in an ultrasonic cleaner, polished and etched with 0.5 M EDTA for 2 minutes to expose dentin tubule orifices. The samples were randomly divided into 3 groups: Group 1: control, Group 2: 2% strontium chloride and Group 3:8% pro-argin. The treatment consisted of application with the test dentifrices to the dentin discs followed by preparation for scanning electron microscopic examination. Results: The numbers of dentinal tubules open, partially occluded and completely occluded were counted and statistical analysis was obtained using Post-Hoc ANOVA test. Group 3 i.e. 8% arginine and calcium carbonate group showed highest complete tubule, with a statistically significant difference from group 1 and group 2. Conclusion: Proargin technology appears more promising in providing immediate relief as well as could be more effective on further application than strontium chloride based formulation. [Mayur P NJIRM 2016; 7(6): 85-92]


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