Developing and evaluating polygenic risk prediction models for stratified disease prevention

Nature Reviews Genetics 17, 392 (2016). doi:10.1038/nrg.2016.27

Authors: Nilanjan Chatterjee, Jianxin Shi & Montserrat García-Closas

Knowledge of genetics and its implications for human health is rapidly evolving in accordance with recent events, such as discoveries of large numbers of disease susceptibility loci from genome-wide association studies, the US Supreme Court ruling of the non-patentability of human genes, and the development

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