Nature Reviews Genetics 17, 376 (2016). doi:10.1038/nrg.2016.70
Author: Bryony Jones
A new single-molecule based assay can identify and map concurrent modifications on individual histones. The team behind this approach were able to identify truly bivalent nucleosomes that harboured both repressive and activating marks, and map their genomic location.Nucleosomal histones can be chemically modified at
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