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ΑΛΕΞΑΝΔΡΟΣ Γ. ΣΦΑΚΙΑΝΑΚΗΣ at Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174 - 11 minutes ago
Preclinical findings on the potential of intranasal neuropeptide Y for treating hyperarousal features of PTSD Thu Jun 27, 2019 21:13 by Chiso Nwokafor, Lidia I. Serova, Esther L. Sabban via Annals of the New York Academy of Sciences [image: Annals of the New York Academy of Sciences Preclinical findings on the potential of intranasal neuropeptide Y for treating hyperarousal features of PTSD] In this study, we examined the effect of acoustic startle by itself on gene expression of components of the CRH and glucocorticoid receptor (GR) system and NPY receptor subtypes in both the mediob... more »
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ΑΛΕΞΑΝΔΡΟΣ Γ. ΣΦΑΚΙΑΝΑΚΗΣ at Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174 - 12 minutes ago
Chlorogenic Acid Alleviates Thiram-Induced Tibial Dyschondroplasia by Modulating Caspases, BECN1 Expression and ECM Degradation 03:00 by Jialu Zhang via MDPI Publishing *IJMS, Vol. 20, Pages 3160: Chlorogenic Acid Alleviates Thiram-Induced Tibial Dyschondroplasia by Modulating Caspases, BECN1 Expression and ECM Degradation* International Journal of Molecular Sciences doi: 10.3390/ijms20133160 Authors: Jialu Zhang Shucheng Huang Xiaole Tong Lihong Zhang Xiong Jiang Hui Zhang Khalid Mehmood Jiakui Li Chlorogenic acid (CGA) is a widely applied traditional Chinese medicine ingredient which... more »
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ΑΛΕΞΑΝΔΡΟΣ Γ. ΣΦΑΚΙΑΝΑΚΗΣ at Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174 - 13 minutes ago
Recent Developments in TSPO PET Imaging as A Biomarker of Neuroinflammation in Neurodegenerative Disorders 03:00 by Eryn L. Werry via MDPI Publishing *IJMS, Vol. 20, Pages 3161: Recent Developments in TSPO PET Imaging as A Biomarker of Neuroinflammation in Neurodegenerative Disorders* International Journal of Molecular Sciences doi: 10.3390/ijms20133161 Authors: Eryn L. Werry Fiona M. Bright Olivier Piguet Lars M. Ittner Glenda M. Halliday John R. Hodges Matthew C. Kiernan Clement T. Loy Jillian J. Kril Michael Kassiou Neuroinflammation is an inflammatory response in the brain and spina... more »
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ΑΛΕΞΑΝΔΡΟΣ Γ. ΣΦΑΚΙΑΝΑΚΗΣ at Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174 - 13 minutes ago
Aristolochic Acid and Immunotherapy for Urothelial Carcinoma: Directions for unmet Needs 03:00 by Huang-Yu Yang via MDPI Publishing *IJMS, Vol. 20, Pages 3162: Aristolochic Acid and Immunotherapy for Urothelial Carcinoma: Directions for unmet Needs* International Journal of Molecular Sciences doi: 10.3390/ijms20133162 Authors: Huang-Yu Yang Chih-Chao Yang Chao-Yi Wu Li-Jen Wang Kun-Lin Lu Urothelial carcinoma of the bladder (UCB) and upper tracts (UTUC) used to share management with similar principles. However, their genetic and epigenetic differences along with different responses to i... more »
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ΑΛΕΞΑΝΔΡΟΣ Γ. ΣΦΑΚΙΑΝΑΚΗΣ at Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174 - 13 minutes ago
Cancers, Vol. 11, Pages 906: Aerosolization of Nanotherapeutics as a Newly Emerging Treatment Regimen for Peritoneal Carcinomatosis 03:00 by Molood Shariati via MDPI Publishing *Cancers, Vol. 11, Pages 906: Aerosolization of Nanotherapeutics as a Newly Emerging Treatment Regimen for Peritoneal Carcinomatosis* Cancers doi: 10.3390/cancers11070906 Authors: Molood Shariati Wouter Willaert Wim Ceelen Stefaan C. De Smedt Katrien Remaut Recent advances in locoregional chemotherapy have opened the door to new approaches for the clinical management of peritoneal carcinomatosis (PC) by facilita... more »
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ΑΛΕΞΑΝΔΡΟΣ Γ. ΣΦΑΚΙΑΝΑΚΗΣ at Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174 - 14 minutes ago
IJMS, Vol. 20, Pages 3163: mRNA Engineering for the Efficient Chaperone-Mediated Co-Translational Folding of Recombinant Proteins in Escherichia coli 03:00 by Le Minh Bui via MDPI Publishing *IJMS, Vol. 20, Pages 3163: mRNA Engineering for the Efficient Chaperone-Mediated Co-Translational Folding of Recombinant Proteins in Escherichia coli* International Journal of Molecular Sciences doi: 10.3390/ijms20133163 Authors: Le Minh Bui Almando Geraldi Thi Thuy Nguyen Jun Hyoung Lee Ju Young Lee Byung-Kwan Cho Sun Chang Kim The production of soluble, functional recombinant proteins by enginee... more »
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ΑΛΕΞΑΝΔΡΟΣ Γ. ΣΦΑΚΙΑΝΑΚΗΣ at Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174 - 16 minutes ago
Stomach-churning footage shows a TICK lodged deep inside a 50-year-old's ear which a doctor spotted after she complained of tinnitus The Thai woman sought help from doctors for the ringing noise in her ear A specialist peered inside the 50-year-old woman's ear and saw the arachnid The unidentified woman went to the Buddhachinaraj Hospital in Phitsanulok By STEPHEN MATTHEWS HEALTH EDITOR FOR MAILONLINE PUBLISHED: 10:08 BST, 28 June 2019 | UPDATED: 10:35 BST, 28 June 2019 e-mail View comments Gruesome footage shows a live tick lodged deep inside the ear of a woman who thought she just... more »
Journal of Plastic, Reconstructive & Aesthetic Surgery
ΑΛΕΞΑΝΔΡΟΣ Γ. ΣΦΑΚΙΑΝΑΚΗΣ at Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174 - 19 minutes ago
Postoperative Levator Function Change in Patients with Unilateral Myogenic versus Aponeurotic Blepharoptosis To compare the change in levator function (LF) after levator resection in patients with unilateral myogenic (MP) and aponeurotic ptosis (AP). Journal of Plastic, Reconstructive & Aesthetic Surgery Thu Jun 27, 2019 03:00 Reappraisal of giant basal cell carcinoma: clinical features and outcomes Giant basal cell carcinoma (GBCC) is a rare subgroup of basal cell carcinomas with diameter >5cm. Current evidence about determining factors is conflicting, suggesting patient neglect on on... more »
JAMA Facial Plastic Surgery
ΑΛΕΞΑΝΔΡΟΣ Γ. ΣΦΑΚΙΑΝΑΚΗΣ at Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174 - 24 minutes ago
Remove ads Is There a Selfie Epidemic? Chen et al should be commended for this novel study, which attempts to directly relate the current landscape of social media to the acceptance of cosmetic surgery. Their findings that social media investment had a positive effect on the consideration of surgery corroborates the rising trend noticed among facial plastic surgeons. The discussion provided on the negative effect of social media and, more specifically, selfies highlights the need to better understand the underlying motives and characteristics... JAMA Facial Plastic Surgery Online Fir... more »
British Association of Plastic Surgeons
ΑΛΕΞΑΝΔΡΟΣ Γ. ΣΦΑΚΙΑΝΑΚΗΣ at Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174 - 24 minutes ago
The outcome of rhinoplasty in patients undergoing autospreader flaps without notable dorsal hump reduction: A Clinical Trial Publication date: Available online 28 June 2019Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Amir A. Sazgar, Nargess Razmara, Ali Razfar, Amir K. Sazgar, Amin AmaliSummaryBackgroundReconstruction of the nasal midvault is an important component of successful rhinoplasty outcomes. Use of the autospreader flap is a beneficial technique for preserving the middle vault. In the present study, we evaluated the aesthetic and functional outco... more »
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ΑΛΕΞΑΝΔΡΟΣ Γ. ΣΦΑΚΙΑΝΑΚΗΣ at Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174 - 25 minutes ago
Breast reconstruction with Superior Gluteal Artery Perforator Free Flap: 8 years of experience. via British Association of Plastic Surgeons [image: elsevier-non-solus.png] Publication date: Available online 28 June 2019 *Source:* Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): Giovanni Zoccali, Maleeha Mughal, Lolade Giwa, Paul Roblin, Jian Farhadi Abstract IntroductionThe SGAP flap represents an alternative for autologous breast reconstruction when DIEP is not available. In this article, we report eight years' experience in breast reconstruction using SGAP free fla... more »
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ΑΛΕΞΑΝΔΡΟΣ Γ. ΣΦΑΚΙΑΝΑΚΗΣ at Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174 - 25 minutes ago
A simple, effective, universal, and reusable osteotomy tool for jaw reconstructions with microvascular fibula-transplants via British Association of Plastic Surgeons [image: elsevier-non-solus.png] Publication date: Available online 28 June 2019 *Source:* Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): Simon Meyer, Jan-Michaél Hirsch, Christoph S. Leiggener, Hans-Florian Zeilhofer, Florian M. Thieringer Summary BackgroundPrecise, expensive individual saw guides are used with increasing frequency for the reconstruction of mandibular defects with fibular grafts. In th... more »
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ΑΛΕΞΑΝΔΡΟΣ Γ. ΣΦΑΚΙΑΝΑΚΗΣ at Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174 - 26 minutes ago
Reappraisal of giant basal cell carcinoma: clinical features and outcomes via British Association of Plastic Surgeons [image: elsevier-non-solus.png] Publication date: Available online 28 June 2019 *Source:* Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): Deemesh Oudit, Hoang Pham, Titus Grecu, Clare Hodgson, Megan E. Grant, Andzhela Abu Rashed, Donald Allan, Adele C. Green Abstract BackgroundGiant basal cell carcinoma (GBCC) is a rare subgroup of basal cell carcinomas with diameter >5cm. Current evidence about determining factors is conflicting, suggesting patient ... more »
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ΑΛΕΞΑΝΔΡΟΣ Γ. ΣΦΑΚΙΑΝΑΚΗΣ at Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174 - 27 minutes ago
British Association of Plastic Surgeons, Reappraisal of giant basal cell carcinoma: clinical features and outcomes Publication date: Available online 28 June 2019Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Deemesh Oudit, Hoang Pham, Titus Grecu, Clare Hodgson, Megan E. Grant, Andzhela Abu Rashed, Donald Allan, Adele C. GreenAbstractBackgroundGiant basal cell carcinoma (GBCC) is a rare subgroup of basal cell carcinomas with diameter >5cm. Current evidence about determining factors is conflicting, suggesting patient neglect on one hand, and biologically agg... more »
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ΑΛΕΞΑΝΔΡΟΣ Γ. ΣΦΑΚΙΑΝΑΚΗΣ at Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174 - 28 minutes ago
Journal of NeuroEngineering and Rehabilitation - What is the impact of user affect on motor learning in virtual environments after stroke? A scoping review The purported affective impact of virtual reality (VR) and active video gaming (AVG) systems is a key marketing strategy underlying their use in stroke rehabilitation, yet little is known as to how affective c... Journal of NeuroEngineering and Rehabilitation - Latest Articles Thu Jun 27, 2019 03:00 Coordination of reach-to-grasp in physical and haptic-free virtual environments Virtual reality (VR) offers unprecedented opportunity ... more »
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ΑΛΕΞΑΝΔΡΟΣ Γ. ΣΦΑΚΙΑΝΑΚΗΣ at Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174 - 29 minutes ago
International Journal of Clinical Pharmacy, Development of a trigger tool for the detection of adverse drug events in Chinese geriatric inpatients using the Delphi method Abstract Background The global trigger tool is a method of retrospective medical record review that identifies possible harm in hospitalized patients using "triggers". Elderly patients with multiple co-morbid illnesses are especially vulnerable to adverse drug events (ADEs) that have high prevalence rates. Objective The purpose of this study was to develop an appropriate trigger tool to detect ADEs in Chinese geriatr... more »
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ΑΛΕΞΑΝΔΡΟΣ Γ. ΣΦΑΚΙΑΝΑΚΗΣ at Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174 - 29 minutes ago
Analysis of the Risk Factors for Postherpetic Neuralgia 08:32 by S.Karger AG via DRM : Last 10 articles *Background:* Postherpetic neuralgia is the most common complication of herpes zoster, affecting 30% of patients. It seriously affects the quality of life of patients and the curative effect of treatment is limited. So far, researchers do not fully understand the risk factors for postherpetic neuralgia and more research is needed. *Objective:* The aim of this paper was to investigate the risk factors for postherpetic neuralgia and provide reference for clinical diagnosis and treatme... more »
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ΑΛΕΞΑΝΔΡΟΣ Γ. ΣΦΑΚΙΑΝΑΚΗΣ at Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174 - 30 minutes ago
The Impact of Focality and Centricity on Vulvar Intraepithelial Neoplasia on Disease Progression in HIV+ Patients: A 10-Year Retrospective Study 11:41 by S.Karger AG via DRM : Last 10 articles *Background:* The impact of lesion focality and centricity in relation to patient outcome and disease recurrence of vulvar intraepithelial neoplasia (VIN) is an understudied area of research, especially in immunocompromised women. The prevalence and incidence of VIN have increased steadily since the 1980s because of the co-existence of human papillomavirus (HPV) and human immunodeficiency virus ... more »
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ΑΛΕΞΑΝΔΡΟΣ Γ. ΣΦΑΚΙΑΝΑΚΗΣ at Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174 - 32 minutes ago
Psychology Today Blogs, Beyond Religion Reason and science aren't enough to transcend religion. The only way in which the human race will ever transcend religion is by transcending ego-separateness. Psychology Today Blogs 12:18 When Your Child Can't Decide Some children agonize over even small decisions. Teaching indecisive kids about myths and truths of decision-making can help them make up their minds. Psychology Today Blogs 07:42 The Arduous Journey to Self-Love Self-love is essential for psychological and emotional well-being. But what is its true meaning? And why do so many struggl... more »
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Role of Targeted Therapies in Management of Metastatic Urothelial Cancer in the Era of Immunotherapy 03:00 via Current Treatment Options in Oncology Opinion statementDespite significant advances and the approval of immune checkpoint inhibitors, metastatic urothelial carcinoma (mUC) is still very hard to treat and has poor outcomes. Deeper understanding of the molecular underpinnings of mUC has identified potential biomarkers, biologic drivers, and relevant therapy targets. However, targeted therapies in mUC have had significant challenges due to molecular heterogeneity, clonal evoluti... more »
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The rabbit brachial plexus as a model for nerve injury and repair Part 1: Anatomic study of the biceps and triceps innervation Thu Jun 27, 2019 17:41 by Kathleen M. Kollitz, Guilherme Giusti, Patricia F. Friedrich, Allen T. Bishop, Alexander Y. Shin via Microsurgery AbstractPurposeAnimal models can be helpful in evaluating new surgical strategies for brachial plexus reconstruction. While several groups have already used the rabbit brachial plexus to model injury, reports conflict in anatomic detail and do not identify a nerve‐muscle pair to measure motor function recovery after recons... more »
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Journal of Cellular Biochemistry, NCF2, MYO1F, S1PR4, and FCN1 as potential noninvasive diagnostic biomarkers in patients with obstructive coronary artery: A weighted gene co‐expression network analysis A four‐gene signature (NCF2, MYO1F, S1PR4, and FCN1) alone or combined with two risk factors (male sex and hyperlipidemia) could act as a noninvasive diagnostic biomarker for obstructive coronary artery disease (CAD) and ST‐segment elevation myocardial infarction (STEMI). Abstract This study aims to explore the predictive noninvasive biomarker for obstructive coronary artery disease ... more »
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Journal of Personality and Social Psychology, Measuring moral politics: How strict and nurturant family values explain individual differences in conservatism, liberalism, and the political middle. Individuals' political stances tend to place them into the conservative "right," the liberal "left," or the moderate "middle." What might explain this pattern of division? Moral Politics Theory (Lakoff, 1996) holds that political attitudes arise from moral worldviews that are conceptually anchored in contrasting family models—the strict-father and nurturant-parent models—while the political... more »
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Longitudinal changes in bone density in adolescents and young adults with cerebral palsy: a case for early intervention Thu Jun 27, 2019 16:39 by Anne Trinh, Phillip Wong, Michael C Fahey, Justin Brown, Boyd J Strauss, Peter R Ebeling, Peter J Fuller, Frances Milat viaClinical Endocrinology AbstractContextCerebral palsy (CP) is a motor disorder affecting movement, muscle tone and posture due to damage to the fetal or infant brain. The subsequent lack of ambulation, nutritional deficiencies, anticonvulsant use and hormonal deficiencies have been implicated in the low bone mass associat... more »
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MRI and teamworking boost outcome in endometriosis 10:00 via AuntMinnieEurope.com Headlines [image: 2019_06_27_17_36_2569_freeman_mri_endome] In tricky cases of endometriosis, the key to success is the optimum use of... Read more on AuntMinnieEurope.com Related Reading: The 10-minute abdominal MRI scan: Can it become reality? Imaging offers hope to women with fertility problems How to manage female genitourinary malformation 7T MRI successfully images the female pelvis Major Swiss infertility study deserves close scrutiny Original enclosures: 2019_06_27_17_36_2569_freeman_mri_endometrio... more »
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What is new in the psychology of chronic itch? Thu Jun 27, 2019 16:13 by Andrea W. M. Evers, Kaya J. Peerdeman, Antoinette I. M. van Laarhoven via Experimental Dermatology AbstractItch is often regarded as unpleasant or bothersome and is accompanied by symptoms of distress and impairments in daily life. The biopsychosocial model of chronic itch describes how psychological factors can contribute to the improvement or exacerbation of chronic itch and related scratching behavior. Recent research underlines the important role of cognitive‐affective information processing, such as attentio... more »
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Tracing the Lineage of Two Traits Associated with the Coat Protein of the Tombusviridae: Silencing Suppression and HR Elicitation in Nicotiana Species 03:00 by Mustafa Adhab via MDPI Publishing *Viruses, Vol. 11, Pages 588: Tracing the Lineage of Two Traits Associated with the Coat Protein of the Tombusviridae: Silencing Suppression and HR Elicitation in Nicotiana Species* Viruses doi: 10.3390/v11070588 Authors: Mustafa Adhab Carlos Angel Andres Rodriguez Mohammad Fereidouni Lóránt Király Kay Scheets James E. Schoelz In this paper we have characterized the lineage of two traits associat... more »
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Manganese Uptake by A549 Cells is Mediated by Both ZIP8 and ZIP14 03:00 by Ivo F. Scheiber via MDPI Publishing *Nutrients, Vol. 11, Pages 1473: Manganese Uptake by A549 Cells is Mediated by Both ZIP8 and ZIP14* Nutrients doi: 10.3390/nu11071473 Authors: Ivo F. Scheiber Neftali Ortega Alarcon Ningning Zhao The alveolar epithelia of the lungs require manganese (Mn) as an essential nutrient, but also provide an entry route for airborne Mn that can cause neurotoxicity. Transporters involved in Mn uptake by alveolar epithelial cells are unknown. Recently, two members of the Zrt- and Irt-like... more »
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A Novel Bradykinin-Related Peptide, RVA-Thr6-BK, from the Skin Secretion of the Hejiang Frog; Ordorrana hejiangensis: Effects of Mammalian Isolated Smooth Muscle 03:00 by Yue Wu via MDPI Publishing *Toxins, Vol. 11, Pages 376: A Novel Bradykinin-Related Peptide, RVA-Thr6-BK, from the Skin Secretion of the Hejiang Frog; Ordorrana hejiangensis: Effects of Mammalian Isolated Smooth Muscle* Toxins doi: 10.3390/toxins11070376 Authors: Yue Wu Daning Shi Xiaoling Chen Lei Wang Yuan Ying Chengbang Ma Xinping Xi Mei Zhou Tianbao Chen Chris Shaw A novel naturally-occurring bradykinin-related pep... more »
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The Nucleoshuttling of the ATM Protein: A Unified Model to Describe the Individual Response to High- and Low-Dose of Radiation? 03:00 by Elise Berthel via MDPI Publishing *Cancers, Vol. 11, Pages 905: The Nucleoshuttling of the ATM Protein: A Unified Model to Describe the Individual Response to High- and Low-Dose of Radiation?* Cancers doi: 10.3390/cancers11070905 Authors: Elise Berthel Nicolas Foray Mélanie L. Ferlazzo The evaluation of radiation-induced (RI) risks is of medical, scientific, and societal interest. However, despite considerable efforts, there is neither consensual mech... more »
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Influence of Physical Education Teachers on Motivation, Embarrassment and the Intention of Being Physically Active During Adolescence 03:00 by Rubén Trigueros via MDPI Publishing *IJERPH, Vol. 16, Pages 2295: Influence of Physical Education Teachers on Motivation, Embarrassment and the Intention of Being Physically Active During Adolescence* International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16132295 Authors: Rubén Trigueros José M. Aguilar-Parra Adolfo J. Cangas Remedios López-Liria Joaquín F. Álvarez According to a WHO report (2018), more than 80% o... more »
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The Push and Pull of Network Mobility: How Those High in Trait-Level Neuroticism Can Come to Occupy Peripheral Network Positions 03:00 by Eric Gladstone via MDPI Publishing *Behavioral Sciences, Vol. 9, Pages 69: The Push and Pull of Network Mobility: How Those High in Trait-Level Neuroticism Can Come to Occupy Peripheral Network Positions* Behavioral Sciences doi: 10.3390/bs9070069 Authors: Eric Gladstone Kathleen M. O'Connor Wyatt Taylor Field research shows that people's network positions are determined, at least in part, by their traits. For instance, over time, actors higher ... more »
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Association between Genetic Polymorphisms in microRNA Machinery Genes and Risk of Papillary Thyroid Carcinoma Thu Jun 27, 2019 03:00 via Pathology & Oncology Research AbstractEvidence suggests that the microRNAs are involved in tumorigenesis and progression of various types of malignant tumors. Therefore, the aim of current research was to examine association between genetic variants in the miRNA machinery genes and risk of papillary thyroid carcinoma(PTC) in Iranian population. Peripheral blood samples were collected from 120 PTC patients and 130 healthy subjects. Genotyping of polym... more »
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Catheterization and Cardiovascular Interventions, Evaluation of the severity of mitral stenosis in patient with pulmonary hypertension: Role of exercise hemodynamics Abstract Dyspnea due to mitral stenosis (MS) and/or pulmonary hypertension (PHT) in patients who may have both conditions presents a challenging diagnostic dilemma. The hemodynamic response to exercise is probably the most helpful method to arrive at the correct diagnosis and treatment algorithm. In this hemodynamic rounds discussion, we evaluated a patient with MS and PHT prior to the decision for mitral valvuloplasty. K... more »
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Characterisation of the Major Extracellular Proteases of Stenotrophomoas maltophilia and Their Effects on Pulmonary Antiproteases 03:00 by Kevin Molloy via Pathogens *Pathogens, Vol. 8, Pages 92: Characterisation of the Major Extracellular Proteases of Stenotrophomoas maltophilia and Their Effects on Pulmonary Antiproteases* Pathogens doi: 10.3390/pathogens8030092 Authors: Kevin Molloy Stephen G. Smith Gerard Cagney Eugene T. Dillon Catherine M. Greene Noel G. McElvaney Stenotrophomonas maltophilia is an emerging global opportunistic pathogen that has been appearing with increasing pre... more »
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CytoJournal, CellBlockistry: Chemistry and art of cell-block making – A detailed review of various historical options with recent advances Vinod B ShidhamCytoJournal 2019 16(1):12-12 Cell-blocks are paraffin-embedded versions of cytology specimens comparable to the formalin-fixed paraffin-embedded (FFPE) tissue from surgical pathology specimens. They allow various elective ancillary studies on a variety of specimens with enhanced cytopathologic interpretation, including opportunity to perform molecular tests. However, different dictionaries and internet search engines primarily proje... more »
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Immunization of Rabbits with Recombinant Human Cytomegalovirus Trimeric versus Monomeric gH/gL Protein Elicits Markedly Higher Titers of Antibody and Neutralization Activity 03:00 by Xinle Cui via International Journal of Molecular Sciences *IJMS, Vol. 20, Pages 3158: Immunization of Rabbits with Recombinant Human Cytomegalovirus Trimeric versus Monomeric gH/gL Protein Elicits Markedly Higher Titers of Antibody and Neutralization Activity* International Journal of Molecular Sciences doi: 10.3390/ijms20133158 Authors: Xinle Cui Zhouhong Cao Shuishu Wang Michael Flora Stuart P. Adler Mi... more »
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Ibrutinib‐related atrial fibrillation: A single center Australian experience 11:18 by Saad Ezad, Arshad A. Khan, Hooria Cheema, Asma Ashraf, Doan T. M. Ngo, Aaron L. Sverdlov, Nicholas J. Collins via Asia-Pacific Journal of Clinical Oncology AbstractBackgroundIbrutinib increases the risk of atrial fibrillation (AF) and is associated with bleeding tendencies. Reported rates of arrhythmia are variable in different studies. The aim of the current analysis was to evaluate the incidence of AF in a single‐center cohort of patients. MethodsThis analysis was conducted at Hunter New England Loc... more »
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Analysis of pre- and intraoperative clinical for successful operating room extubation after living donor liver transplantation: a retrospective observational cohort study 03:00 by Min Suk Chae, Jong-Woan Kim, Joon-Yong Jung, Ho Joong Choi, Hyun Sik Chung, Chul Soo Park, Jong Ho Choi and Sang Hyun Hong via BMC Anesthesiology - Latest Articles Background Early extubation after liver transplantation is safe and accelerates patient recovery. Patients with end-stage liver disease undergo sarcopenic changes, and sarcopenia is associated with postoperative morbidity and mortality. We invest... more »
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Clinical evaluation of performance, biocompatibility, and safety of vitamin E-bonded polysulfone membrane hemodialyzer compared to non-vitamin E-bonded hemodialyzer Wed Jun 26, 2019 03:00 via Latest Results for Journal of Artificial Organs AbstractThe vitamin E-bonded polysulfone membrane hemodialyzer (ViE™-21) was evaluated in a clinical study for regulatory submission. Seventeen patients on hemodialysis were treated with conventional high-flux hemodialyzers for 2 weeks (Pre-ViE phase) and switched to the ViE-21 for 36 sessions (ViE phase) followed by an additional 2 weeks on convent... more »
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Pollen morphological variation of Berberis L. from Pakistan and its systematic importance Thu Jun 27, 2019 13:34 by Saeed ur Rahman, Shujaul Mulk Khan, Muhammad Zafar, Mushtaq Ahmad, Raees Khan, Sajad Hussain, Muhammad Khalid, Sadaf‐Ilyas Kayani via Microscopy Research and Technique [image: Microscopy Research and Technique Pollen morphological variation of Berberis L. from Pakistan and its systematic importance] Light and scanning electron microscopic investigation of the pollens of 10 Pakistani *Berberis* L. species for the first time. The investigated characters were found useful t... more »
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MALAT1 accelerates the development and progression of renal cell carcinoma by decreasing the expression of miR‐203 and promoting the expression of BIRC5 Thu Jun 27, 2019 21:53 by Haimin Zhang, Wei Li, Wenyu Gu, Yang Yan, Xudong Yao, Junhua Zheng via Cell Proliferation [image: cpr12640-math-0001.png] AbstractObjectiveWe aimed to investigate the roles of the lncRNA MALAT1 in renal cell carcinoma (RCC) progression. MethodsqRT‐PCR was used for the assessment of *BIRC5*, miRNA‐203 and MALAT1 expression. Furthermore, the targeted relationships between miR‐203 and *BIRC5*, as well as MALAT1 ... more »
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Journal of Cellular Biochemistry, lncRNA HNF1A‐AS1 modulates non–small cell lung cancer progression by targeting miR‐149‐5p/Cdk6 lncRNA HNF1A‐AS1 was induced in both NSCLC tumor tissues and cell lines HNF1A‐AS1 induced NSCLC cell proliferation and cell cycle HNF1A‐AS1 induced NSCLC cell migration and invasion. Abstract Growing evidence have shown the important regulation of lncRNAs (long noncoding RNAs) in non–small cell lung cancer (NSCLC). lncRNA hepatocyte nuclear factor 1 homeobox A (HNF1A)‐antisense RNA 1 (AS1), an "oncogene", was reported to regulate human tumors progression. ... more »
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AuntMinnieEurope.com, German group secures top molecular award Researchers from Heidelberg, Germany, have won this year's Image of the Year...Read more on AuntMinnieEurope.comRelated Reading: SNMMI: FET-PET could have answers for brainstem glioma SNMMI: PET/CT may help guide prostate biopsies SNMMI: FDG-PET/CT predicts ovarian cancer survival SNMMI: Germans scoop Image of the Year award SNMMI: New PET tracer detects recurrent prostate cancer AuntMinnieEurope.com Headlines Thu Jun 27, 2019 19:23
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The Laryngoscope An Innovative Approach to Airway Foreign Body Management in an Extremely Premature Neonate This case report is a retrospective review of a challenging though ultimately successful removal of an airway foreign body in a 2‐day‐old premature female born at 23 weeks and 4 days gestation. A segment of a 5‐F surfactant catheter was cut and accidentally dislodged in the distal airway within the lumen of the patient's endotracheal tube. Ultimately, visualization was obtained using a 1.6‐mm KARL STORZ sialoendoscope, and retrieval was performed using sialoendoscopy forceps p... more »
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Microsurgical anatomy of the subcallosal artery Thu Jun 27, 2019 03:00 via Surgical and Radiologic Anatomy AbstractBackground and purposeThe subcallosal artery [SCA, a branch of the anterior communicating artery (ACoA)] is not well described in the literature. However, the memory disorders that can occur after surgical repair of ruptured ACoA aneurysms might be related to infarction of the SCA. The objective of the present study was to perform a thorough anatomical assessment of the SCA. MethodsThe study was carried out over a 6-month period in a University Hospital's anatomy laborato... more »
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Surgical and Radiologic Anatomy, A 1810 skull of Napoleon army's soldier: a clinical–anatomical correlation of steam gun trauma Abstract Introduction In the following article, we are presenting a clinical observation of Baron Larrey. In 1804, Larrey was the inspector general of health, as well as the chief surgeon of the imperial Napoleonic Guard. He participated in all of Napoleon's campaigns. A paleopathological study was performed on a skull from Dupuytren's Museum (Paris) with a long metal stick in the head. We report here a clinical case as well as the autopsy... Surgical and R... more »
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Molecular Neurobiology, Early Sociability and Social Memory Impairment in the A53T Mouse Model of Parkinson's Disease Are Ameliorated by Chemogenetic Modulation of Orexin Neuron Activity Abstract Parkinson's disease (PD) is a multi-layered progressive neurodegenerative disease. Signature motor system impairments are accompanied by a variety of other symptoms such as mood, sleep, metabolic, and cognitive disorders. Interestingly, social cognition impairments can be observed from the earliest stages of the disease, prior to the onset of the motor symptoms. In this study, we investigate... more »
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Sensitive skin is a neuropathic disorder Wed Jun 26, 2019 19:25 by Flavien Huet, Laurent Misery via Experimental Dermatology AbstractSensitive skin is defined by the occurrence of unpleasant sensations such as tingling, burning, tautness, itching or pain. Mechanisms explaining sensitive skin are controversial, and many hypotheses have been proposed. Because sensitive skin is primarily characterized by a wide variety of neuropathic‐like symptoms, it is highly likely that neurosensory dysfunction in the skin represents one of the pathological mechanisms of sensitive skin. This hypothesi... more »
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Carbohydrates in Human Milk and Body Composition of Term Infants during the First 12 Months of Lactation 03:00 by Zoya Gridneva via MDPI Publishing *Nutrients, Vol. 11, Pages 1472: Carbohydrates in Human Milk and Body Composition of Term Infants during the First 12 Months of Lactation* Nutrients doi: 10.3390/nu11071472 Authors: Zoya Gridneva Alethea Rea Wan Jun Tie Ching Tat Lai Sambavi Kugananthan Leigh C. Ward Kevin Murray Peter E. Hartmann Donna T. Geddes Human milk (HM) carbohydrates may affect infant appetite regulation, breastfeeding patterns, and body composition (BC). We investi... more »
Groundwater magnesium had a weak association with lower SBP and DBP of the participants.
Groundwater Chemistry and Blood Pressure: A Cross-Sectional Study in Bangladesh 03:00 by Abu Mohd Naser via MDPI Publishing *IJERPH, Vol. 16, Pages 2289: Groundwater Chemistry and Blood Pressure: A Cross-Sectional Study in Bangladesh* International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16132289 Authors: Abu Mohd Naser Thomas F. Clasen Stephen P. Luby Mahbubur Rahman Leanne Unicomb Kazi M. Ahmed Solaiman Doza Shadassa Ourshalimian Howard H. Chang Jennifer D. Stowell K. M. Venkat Narayan Mohammad Shamsudduha Shivani A. Patel Bethany O'Shea Matthew O. Gri... more »
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Management of Diabetes Mellitus in Normal Renal Function, Renal Dysfunction and Renal Transplant Recipients, Focusing on Glucagon-Like Peptide-1 Agonist: A Review Based upon Current Evidence 03:00 by Shang-Feng Tsai via MDPI Publishing *IJMS, Vol. 20, Pages 3152: Management of Diabetes Mellitus in Normal Renal Function, Renal Dysfunction and Renal Transplant Recipients, Focusing on Glucagon-Like Peptide-1 Agonist: A Review Based upon Current Evidence* International Journal of Molecular Sciences doi: 10.3390/ijms20133152 Authors: Shang-Feng Tsai Cheng-Hsu Chen Diabetes Mellitus (DM) is a... more »
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Effect of Cocoa Products and Its Polyphenolic Constituents on Exercise Performance and Exercise-Induced Muscle Damage and Inflammation: A Review of Clinical Trials 03:00 by Massaro Marika via MDPI Publishing *Nutrients, Vol. 11, Pages 1471: Effect of Cocoa Products and Its Polyphenolic Constituents on Exercise Performance and Exercise-Induced Muscle Damage and Inflammation: A Review of Clinical Trials* Nutrients doi: 10.3390/nu11071471 Authors: Massaro Marika Egeria Scoditti Maria Annunziata Carluccio Antonia Kaltsatou Antonio Cicchella In recent years, the consumption of chocolate and... more »
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Food Insecurity and Geriatric Hospitalization 03:00 by Rachel S. Bergmans via MDPI Publishing *IJERPH, Vol. 16, Pages 2294: Food Insecurity and Geriatric Hospitalization* International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16132294 Authors: Rachel S. Bergmans Briana Mezuk Kara Zivin Food insecurity (FI) has been associated with hospitalization, although the pathways underlying this relationship are poorly understood, in part due to the potential for a bidirectional relationship. This study aimed to determine associations of FI with concurrent and future ... more »
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Παιδί και εθισμός στο κινητό τηλέφωνο: Πώς μπορούν να παρέμβουν εποικοδομητικά οι γονείς Οι μισοί από τους εφήβους είναι εξαρτημένοι από το κινητό τους τηλέφωνο και το ίδιο ποσοστό γονέων αναγνωρίζει μεν το πρόβλημα, αλλά δεν ξέρει τι μπορεί να κάνει, σύμφωνα με μια επιστημονική μελέτη. The post Παιδί και εθισμός στο κινητό τηλέφωνο: Πώς μπορούν να παρέμβουν εποικοδομητικά οι γονείς appeared first on Iatropedia. Iatropedia.gr 08:00
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Randomized clinical study to compare negative pressure wound therapy with simultaneous saline irrigation and traditional negative pressure wound therapy for complex foot infections Abstract The aim of this study was to compare the efficacy of different negative pressure wound therapy (NPWT) devices and NPWT with and without simultaneous irrigation in patients admitted to hospital with moderate and severe foot infections. Ninety patients were randomized in a 12‐week prospective, randomized noninferiority trial to compare wound healing in patients with moderate and severe infected foo... more »
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Human Mutation, TAB2 c.1398dup variant leads to haploinsufficiency and impairs extracellular matrix homeostasis Abstract Transforming growth factor β‐activated kinase 1 (TAK1) mediates multiple biological processes through the nuclear factor κ‐light‐chain‐enhancer of activated B cells (NF‐κB) and the mitogen‐activated protein kinase (MAPK) signaling pathways. TAK1 activation is tightly regulated by its binding partners (TABs). In particular, binding with TAB2 is crucial for cardiovascular development and extracellular matrix (ECM) homeostasis. In our previous work, we reported a nov... more »
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Transplant Infectious Disease, Infectivity and stability of hepatitis C virus in different perfusion solutions Abstract Background Due to organ shortage transplantation of organs from HCV (hepatitis C virus) viremic donors into HCV negative individuals is getting more and more accepted. However, transmission of HCV to the host is nearly universal. Until now it is unknown if preservation solutions (PS) might alter infectivity and stability of HCV in the transplant setting. Therefore, seven different preservation solutions (PS) with variable composition were tested in vitro for their ... more »
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Cancers, Vol. 11, Pages 903: Diagnostic Leukapheresis Enables Reliable Transcriptomic Profiling of Single Circulating Tumor Cells to Characterize Inter-Cellular Heterogeneity in Terms of Endocrine Resistance Cancers, Vol. 11, Pages 903: Diagnostic Leukapheresis Enables Reliable Transcriptomic Profiling of Single Circulating Tumor Cells to Characterize Inter-Cellular Heterogeneity in Terms of Endocrine Resistance Cancers doi: 10.3390/cancers11070903 Authors: Florian Reinhardt André Franken Franziska Meier-Stiegen Christiane Driemel Nikolas H. Stoecklein Johannes C. Fischer Dieter Nie... more »
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FLNC pathogenic variants in patients with cardiomyopathies: Prevalence and genotype‐phenotype correlations Abstract Pathogenic variants in FLNC encoding filamin C have been firstly reported to cause myopathies, and were recently linked to isolated cardiac phenotypes. Our aim was to estimate the prevalence of FLNC pathogenic variants in subtypes of cardiomyopathies and to study the relations between phenotype and genotype. DNAs from a cohort of 1150 unrelated index‐patients with an isolated cardiomyopathy (700 hypertrophic, 300 dilated, 50 restrictive cardiomyopathies, and 100 left v... more »
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Viruses, Vol. 11, Pages 588: Tracing the Lineage of Two Traits Associated with the Coat Protein of the Tombusviridae: Silencing Suppression and HR Elicitation in Nicotiana Species Viruses, Vol. 11, Pages 588: Tracing the Lineage of Two Traits Associated with the Coat Protein of the Tombusviridae: Silencing Suppression and HR Elicitation in Nicotiana Species Viruses doi: 10.3390/v11070588 Authors: Mustafa Adhab Carlos Angel Andres Rodriguez Mohammad Fereidouni Lóránt Király Kay Scheets James E. Schoelz In this paper we have characterized the lineage of two traits associated with the ... more »
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