3D genome shows its stripes in gene-rich regions

3D genome shows its stripes in gene-rich regions

3D genome shows its stripes in gene-rich regions, Published online: 20 February 2019; doi:10.1038/s41576-019-0102-x

Chromosomal inversions that relocate a limb enhancer establish patterns of asymmetric chromatin contacts, so-called architectural stripes, that result in ectopic gene expression and congenital limb phenotypes, according to a study in Nature Cell Biology.

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