A Prospective Longitudinal Study of Trajectories of Depressive Symptoms after Dysvascular Amputation

Publication date: Available online 31 December 2018

Source: Archives of Physical Medicine and Rehabilitation

Author(s): Ann Marie Roepke, Aaron P. Turner, Alison W. Henderson, Simon B. Goldberg, Daniel C. Norvell, Joseph M. Czerniecki, Rhonda M. Williams

Abstract

Objective

Characterize the course of depressive symptoms during the first year after dysvascular amputation and identify factors that predict symptom trajectories.

Design

Prospective cohort study of individuals undergoing lower extremity amputation (LEA), surveyed at 4 timepoints (peri-operative period, 6 weeks, 4 months, and 12 months post-amputation). Multilevel modeling was used to describe and predict trajectories.

Setting

Four Veterans Affairs medical centers, a university hospital, and a level I trauma center.

Participants

Participants (N = 141; 74% retention) were a consecutive sample, eligible if they were undergoing their first unilateral LEA secondary to dysvascular disease.

Interventions

Not applicable

Main Outcome Measure

Patient Health Questionnaire-9

Results

Approximately 40% of participants endorsed at least moderate depressive symptoms at perioperative baseline. Individuals with greater depressive symptoms in the perioperative period concurrently reported greater pain, poorer self-rated health, and prior mental health treatment. In the first 6 weeks after amputation there was a substantial improvement in depressive symptoms, especially among individuals with greater symptoms at baseline. Depressive symptoms were generally stable after 6 weeks. None of the covariates assessed significantly predicted trajectories of depressive symptom improvement.

Conclusions

Watchful waiting may be the most appropriate course of action for many patients in the first six weeks after amputation. After six weeks, however, symptom levels tend to stabilize, suggesting that active intervention is called for if patients remain depressed at this point. Some patients may benefit from more proactive intervention, such as those with prior mental health treatment histories.

from Rehabilitation via xlomafota13 on Inoreader http://bit.ly/2GRxxv0
via IFTTT