Physiological and Perceived Exertion Responses during Exercise: Effect of β-blockade

Purpose This study investigated the effect of β-blockade on physiological and perceived exertion (RPE) responses during incremental treadmill exercise. Methods Sixteen healthy participants (n=8 men; age 25.3±4.6 y) performed a maximal treadmill exercise test following ingestion of 100 mg Metoprolol or placebo, with a double-blind, randomised and counter-balanced design. Heart rate (HR), ventilatory and gas exchange variables were measured continuously, and participants reported RPE at the end of each minute. Physiological and RPE responses during each condition were compared at the ventilatory threshold (VT), respiratory compensation point (RCP) and at maximal exercise using repeated measures ANOVA. Linear regression modelled relationships between perceived exertion and physiological variables. Results The HR and V[Combining Dot Above]O2 at the VT, RCP and maximal exercise were all significantly lower following β-blockade (p<.05 however when standardised to within condition peak values differences were no longer significant. the rpe associated with vt was higher following vs p but lower at maximal exercise vs. increases in relative hr greater and remained significant expressed hr. there difference growth of relationship between v dot above across conditions though origin conclusions although resulted a reduction exercising for given intensity unchanged. not affected by results provide evidence that is useful reliable measure testing prescription patients prescribed therapy. correspondence: braden l mitchell school health sciences university south australia gpo box adelaide sa email: braden.mitchell blm supported an australian government research training program scholarship. this study are presented clearly honestly without fabrication falsification or inappropriate data manipulation. present do constitute endorsement acsm. accepted publication november american college sports medicine>

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