EEG coherence in a mental arithmetic task performance in first episode schizophrenia and schizoaffective disorder

Current theories of schizophrenia (SZ) have emphasized that the pathophysiology arises from a 'dysconnectivity' between and within cortical areas of the brain (Friston, 1999, Uhlhaas and Singer, 2010, Stephan et al., 2009). Studies of functional connectivity in patients with schizophrenia using PET and functional MRI data both during cognitive tasks (Potkin and Ford, 2009 for a review) and at rest (for a review see Greicius, 2008) vastly support this hypothesis. However, less attention has been paid to the particular disorders within the schizophrenia spectrum.

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