Opioid prescription patterns for adults with longstanding disability and inflammatory conditions compared to other users, using a nationally representative sample

Publication date: Available online 10 August 2018

Source: Archives of Physical Medicine and Rehabilitation

Author(s): Yuan Hong, Marco Geraci, Margaret A. Turk, Bryan L. Love, Suzanne W. McDermott

Abstract

Objectives

To investigate the opioid prescription patterns for adults with longstanding physical disability and inflammatory conditions, compared to a mixed group of other opioid users, after excluding cancer patients.

Design

Nationally representative cross-sectional study, 2010-2014

Setting

Medical Expenditure Panel Survey (MEPS)

Participants

The subjects were adults who participated in MEPS and had at least one opioid prescription, did not have cancer, and were between 18 years and 64 years of age.

The subjects were grouped as: longstanding physical disability (group 1), inflammatory conditions (group 2) and a mixed group with at least one opioid prescription during the 2 year study period (comparison group). Subjects with both groups of conditions were excluded.

Interventions

Not applicable.

Main outcome measure(s)

Morphine milligram equivalent (MME) doses for each participant were cumulated over a two-year panel period.

Results

By using quantile regression, Cumulative MME in group 1 and 2 was higher than the comparison group across all the centiles, and differences between condition groups and comparison group became larger in higher centiles. Subjects in group 1 had the highest cumulative MME in 75^th and 90^th centiles after controlling for other covariates.

Conclusions

This study documented the opioid prescription patterns for patients with longstanding physical disability or inflammatory conditions. All indexed groups (group 1 and 2) had higher MME use compared to the comparison group.

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