Objectives: The only available treatment for celiac disease (CD) is the gluten-free diet. It is unclear whether the presence of gluten in oral hygiene products and cosmetics that are applied on the mouth is a reason of concern for CD patients. The aim of this study was to test the level of gluten contamination in oral hygiene and cosmetic products available in the Italian market. Methods: A total of 66 products (toothpastes = 37; dental tablets = 2; mouthwashes = 5; lip-balms = 10; lipsticks = 12) labelled gluten-free or with unknown gluten content were randomly collected from different supermarkets and pharmacies. The gluten quantification was determined by the R5 ELISA method approved by EU regulations. Results: Out of 66 oral hygiene and cosmetics, 62 products (94%) were found to be gluten-free (gluten level 20 ppm (toothpastes: 20.7 ppm, 31.4 ppm, and 35 ppm; lipstick: 27.4 ppm). None of the selected products had ingredient derived from wheat, barley, or rye. Conclusions: Gluten contamination is currently not an issue in a wide array of cosmetic and oral hygiene products that are commonly on the market. Address correspondence and reprint requests to Anil K. Verma, M.Sc., Celiac Disease Research Laboratory, Department of Pediatrics, Marche Polytechnic University, Ancona, 60123, Italy (e-mail: anilkrvermaa@gmail.com, a.k.verma@pm.univpm.it) Received 6 June, 2018 Accepted 19 July, 2018 Supplemental digital content is available for this article. Direct URL citations appear in the printed text, and links to the digital files are provided in the HTML text of this article on the journal's Web site (www.jpgn.org). Source of Funding and conflict of interest: This study has not received any fund for any funding body. Carlo Catassi and Elena Lionetti are scientific consultants to Dr Schär's, all other authors declare no conflict of interest. © 2018 by European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology,
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