Auditory gamma oscillations predict global symptomatic outcome in the early stages of psychosis: a longitudinal investigation

The gamma-band auditory steady-state response (ASSR) is hypothesized to be a useful biomarker for psychosis (Uhlhaas and Singer, 2010). Kwon et al. (1999) performed the first study of 40-Hz ASSR in patients with schizophrenia using electroencephalography (EEG) and demonstrated a reduced power and synchronization in response to 40-Hz stimulation, but not to the 20-Hz stimulation, in these patients. This initial finding has been replicated in many studies using EEG (Brenner et al., 2003; Hamm et al., 2015; Hirano et al., 2015; Kirihara et al., 2012; Light et al., 2006; Spencer et al., 2008; Tada et al., 2016) or magnetoencephalography (MEG; Edgar et al., 2014; Teale et al., 2008; Tsuchimoto et al., 2011; Vierling-Claassen et al., 2008; Wilson et al., 2008).

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