Τρίτη 24 Ιουλίου 2018

Integrative analysis of single-cell genomics data by coupled nonnegative matrix factorizations [Genetics]

When different types of functional genomics data are generated on single cells from different samples of cells from the same heterogeneous population, the clustering of cells in the different samples should be coupled. We formulate this "coupled clustering" problem as an optimization problem and propose the method of coupled nonnegative...

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