Reply to “Diagnosing Neuropathy in an Obese Patient”: Measuring neuropathy in obese populations: Nerve conduction studies

We appreciate the comments by Drs. Bodofsky and Carter (Bodofsky and Carter, 2018) pertaining to our article "Better diagnostic accuracy of neuropathy in obesity: A new challenge for neurologists" (Callaghan et al., 2018). We agree that the diagnostic characteristics of the Utah Early Neuropathy Score (UENS) and the Michigan Neuropathy Screening Instrument (MNSI) examination scores may be overestimated secondary to incorporation bias as pointed out in our limitations section. We also agree that the confidence intervals of our AUC estimates do not allow definitive comparisons for all of the neuropathy measures tested.

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