MEG revealed new functional hub of atypical brain network in autism spectrum disorders

Autism spectrum disorders (ASD) are neurodevelopmental disorders with continuous disturbance of cognitive flexibility and social communication, restricted, repetitive patterns of interests and behavior (O'Connor, 2012; Schelinski et al., 2016). Emerging evidence has been almost proving the idea that ASD is a condition of altered brain functional connectivity, especially in resting-state. Previous brain connectivity studies using functional magnetic resonance imaging (fMRI) in young adults with ASD showed reduction of resting-state connectivity at the medial prefrontal cortex (mPFC), the anterior hub of the default-mode network (DMN), and the posterior cingulate cortex (PCC), the posterior hub of the DMN (Kennedy and Courchesne, 2008, Di Martino et al, 2009).

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