Reply to “Comments on Clinical classification criteria for neurogenic claudication caused by lumbar spinal stenosis. The N-CLASS criteria”

We thank Safiri et al. for their careful review of our paper and their interest in the process we used to develop and validate the Clinical classification criteria for neurogenic claudication caused by lumbar spinal stenosis (N-CLASS) criteria [1]. We agree with them that full validation of the N-CLASS criteria requires assessment in an independent sample. They highlight issues of model uncertainty in creating the N-CLASS criteria and how studies can better accomplish this. In our article, we used a multicenter, but modest-sized, sample of 209 patients to create a simple clinical score using five predictor variables.

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