Παρασκευή 23 Μαρτίου 2018

Myocellular Responses to Concurrent Flywheel Training during 70 Days of Bed Rest

Purpose This investigation evaluated myocellular responses to an integrated resistance and aerobic training program (SPRINT) during 70 days of bed rest. Methods Training was six days per week on a small-footprint gravity-independent flywheel resistance and aerobic device (FLY); three days of maximal flywheel supine quadriceps and calf exercises with continuous rowing separated by 4-6 hours, and three days of interval rowing. Vastus lateralis (VL) and soleus (SOL) muscle biopsies were obtained from eight healthy males (age=28±4 y, BMI=25±3 kg•m−2, VO2max=42±6 ml•kg−1•min−1) before and after 6° head-intrdown tilt bed rest. VL and SOL myosin heavy chain (MHC) I and IIa single muscle fiber size and functional characteristics, as well as overall fiber type distribution, capillarization, and metabolic enzyme activities were evaluated. Results In the VL, MHC I size and power (absolute and normalized) were preserved. MHC IIa fibers hypertrophied (+6%, P

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