An evaluation of kurtosis beamforming in magnetoencephalography to localize the epileptogenic zone in drug resistant epilepsy patients

The aim of epilepsy surgery is to remove the epileptogenic zone (EZ), i.e. the region whose removal ensures postoperative seizure freedom (Engel, 1996; Lüders et al., 2006). Hypotheses about the location of the EZ are typically generated on the basis of the patient's clinical history, as well as electroencephalography (EEG), neuropsychological and neuroimaging assessments (Engel, 1996; Lüders et al., 2006; Dorfer et al., 2015). Approximately 15-25% of patients yield inconclusive or non-localizing results (Zumsteg et al., 2000; Carrette et al., 2010) often meaning that additional invasive testing is required (Blount et al., 2008).

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