AbstractPurposeTo examine the influence of reallocating time spent at different objectively measured physical activity (PA) behaviours on markers of systemic inflammation in older women with different levels of metabolic risk.MethodsAccelerometer-based monitoring of PA was conducted in a population of community-dwelling older women (n = 111; age = 65-70 yr) for determination of daily sedentary time, time in light (LPA) and moderate-to-vigorous physical activity (MVPA). Blood samples were collected for the assessment of the systemic inflammatory markers CRP, fibrinogen and adiponectin. Metabolic risk was assessed by standardized procedures based on definitions for the metabolic syndrome. Data were analysed by linear regression models based on isotemporal substitution analysis.ResultsReallocating 30 minutes of sedentary time with either time in LPA (β = -0.47; p
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