Epileptiform and periodic EEG activities induced by rapid sevoflurane anaesthesia induction

Sevoflurane is a fluorinated inhalated anaesthetic introduced into clinical practice in the 1990's. It is now widely used in both adults and children because of its rapid onset and short-lasting activity, pleasant odour and non-pungency (Eger 1994; Lerman et al., 1994). A rapid increase in the inspiratory concentration of sevoflurane, however, has been demonstrated to be associated with a transient hyperdynamic reaction in adult patients during controlled mild hypocapneic hyperventilation (Vakkuri et al., 1999).

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