Widespread covariation of early environmental exposures and trait-associated polygenic variation [Psychological and Cognitive Sciences]

Although gene–environment correlation is recognized and investigated by family studies and recently by SNP-heritability studies, the possibility that genetic effects on traits capture environmental risk factors or protective factors has been neglected by polygenic prediction models. We investigated covariation between trait-associated polygenic variation identified by genome-wide association studies (GWASs) and...

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