Reply to Pluss et al.: The strength of PEMapper/PECaller lies in unbiased calling using large sample sizes [Biological Sciences]

In a recent Letter in PNAS (1), Plüss et al. compare the speed and accuracy of the Burrows–Wheeler aligner (BWA) (2)/Genome Analysis Toolkit (GATK) (3) best-practices pipeline (4), against our PEMapper/PECaller pipeline (5), as well as against a commercially available, but un–peer-reviewed method called GENALICEMAP (genalice.com). This test was conducted...

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