Need for speed in accurate whole-genome data analysis: GENALICE MAP challenges BWA/GATK more than PEMapper/PECaller and Isaac [Biological Sciences]

In the current high-throughput genomics era, efficient and accurate analysis of large-scale whole-genome sequencing (WGS) data constitutes a computational bottleneck. Johnston et al. (1) introduce the PEMapper/PECaller software package for short-read WGS alignment and variant calling, promising faster analyses with reduced output file sizes and "nearly identical (or better)" variant...

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