Impact of moderate-intensity and vigorous-intensity physical activity on mortality.

Purpose: Physical activity guidelines recommend at least 150 min of moderate-intensity physical activity (MPA), 75 min of vigorous-intensity physical activity (VPA), or combination of MPA and VPA. However, few epidemiological studies have examined whether the general population can derive equal health benefits from MPA or VPA. This study examined the associations of different activity intensities with mortality. Methods: In this prospective cohort study, a total of 83,454 community-dwelling Japanese who answered a questionnaire in 2000-2003 were followed for all-cause mortality through 2012. Subjects were classified into four groups by physical activity guidelines and also by the proportion of VPA to total MVPA, i.e., physically inactive, physically active without any VPA (0% VPA), and active with some VPA (less than 30%) or with more VPA (30% or more). Hazard ratios (HR) of all-cause mortality were calculated with adjustment for potential confounders including PA volume. Results: During 894,718 person-years of follow-up, 8,891 deaths were identified. Compared with physically inactive subjects, the adjusted HRs for all-cause mortality were 0.90 (95% CI: 0.75-1.08), 0.78 (0.68-0.89), and 0.74 (0.64-0.86) among men, and 0.78 (0.62-0.99), 0.66 (0.54-0.79), and 0.64 (0.50-0.81) among women for "0% VPA," "less than 30%," and "30% or more," respectively. In addition, men in the "30% or more" group showed somewhat lower mortality risk than "0% VPA" men (0.81, 0.66-1.01), but women did not. Conclusions: Meeting the guidelines in either pattern of physical activity is important for lowering mortality risk. In addition, compared with subjects who did not engage in any VPA, there was a suggestion that those who participated in VPA may experience lower risks, especially for men. (C) 2017 American College of Sports Medicine

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