Effects of Creatine and Carbohydrate Loading on Cycling Time Trial Performance.

Introduction: Creatine- and carbohydrate-loading are dietary strategies used to enhance exercise capacity. This study examined the metabolic and performance effects of a combined creatine and CHO-loading regiment on time-trial (TT) cycling bouts. Methods: Eighteen well-trained (~65mL[BULLET OPERATOR]kg-1[BULLET OPERATOR]min-1 VO2peak) males completed three performance trials (PT) comprised of a 120-km cycling TT interspersed with alternating 1- and 4-km sprints (6 sprints each) performed every 10-km followed by an inclined ride to fatigue (~90% VO2peak). Subjects were pair-matched into either creatine-loaded (20g[BULLET OPERATOR]d-1 for 5d + 3 g[BULLET OPERATOR]d-1 for 9d; CR) or placebo (PLA) groups (n=9) following the completion of PT1. All subjects undertook a cross-over application of the carbohydrate interventions, consuming either moderate-(6g[BULLET OPERATOR]kg-1 body mass (BM)/d; MOD) or CHO-loaded (12g[BULLET OPERATOR]kg-1 BM/d; LOAD) diets before PT2 and PT3. Muscle biopsies were taken prior to PT1, 18h post-PT1, and prior to both PT2 and PT3. Results: No significant differences in overall TT or inclined ride times were observed between intervention groups. PLA+LOAD improved power above baseline (P

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