Effects of the α-Adrenergic, Kisspeptinergic, and Melatonin Systems on the Morphofunctional State of Cells of the Adrenal Cortex in Mature Rats

In experiments on young mature (three-month-old) albino rats, we examined the effects of the α-adrenergic, kisspeptinergic, and melatonin systems on the morphofunctional state of the adrenal cortex. Manifestations of the effects of these regulatory factors in the three zones of the adrenal cortex were dissimilar. For the glomerular zone, the state of the α-adrenergic system and high levels of melatonin played a crucial role, while the role of the kisspeptinergic system was secondary. Kisspeptinergic regulation played a major role in the modulation of the state of cells in the fascicular zone. Simultaneously, spongyocytes of this zone were inactivated upon blocking of both the kisspeptinergic and α-adrenergic systems. Adequate levels of the activity of the α-adrenergic and kisperpinergic systems were simultaneously necessary to maintain the sufficient state of spongyocytes in the reticular zone of the adrenal cortex, while effects of melatonin were not decisively important.

from Physiology via xlomafota13 on Inoreader http://ift.tt/2fuYKXg
via IFTTT