MRG15-mediated tethering of PALB2 to unperturbed chromatin protects active genes from genotoxic stress [Genetics]

The partner and localiser of BRCA2 (PALB2) plays important roles in the maintenance of genome integrity and protection against cancer. Although PALB2 is commonly described as a repair factor recruited to sites of DNA breaks, recent studies provide evidence that PALB2 also associates with unperturbed chromatin. Here, we investigated the...

from Genetics via xlomafota13 on Inoreader http://ift.tt/2vfrq9R
via IFTTT