Epileptic spikes in Rasmussen’s encephalitis: migratory pattern and short-term evolution. A MEG study

Rasmussen's encephalitis (RE) is a severe immunomediated disorder that typically begins in childhood with the progressive atrophy of one cerebral hemisphere, worsening neurological deficits, and refractory epilepsy (Bien et al., 2002a; Bien et al., 2005; Olson et al., 2013). Although it can occasionally have atypical features, it usually has three stages that occur within months or a few years of each other: after a non-specific prodromal period, the acute phase is characterised by progressive cortical dysfunction with frequent focal onset seizures or epilepsia partialis continua (EPC), and the late stage is characterised by neurological and cognitive deficits and persistent seizures (Olson et al., 2013).

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