Within the last year, 2 patients presented to our Southern California allergy clinic with a history of severe anaphylactic reactions (one with loss of consciousness and the other with urticaria, laryngeal edema, and near syncope) after the initial consumption of chapulines (roasted grasshopper from Oaxaca, Mexico) despite no previous occupational or natural exposure to chapulines and no history of having ever eaten chapulines before. This is the first documented report of anaphylaxis to chapuline in the medical literature.
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