Eosinophilic esophagitis (EoE) is an increasingly recognized eosinophilic gastrointestinal disorder that affects children and adults, with a prevalence of 5 per 10,000 inhabitants in Europe and the United States.1 Food antigens trigger more than 90% of cases; however, data suggest that aeroallergens may also play a pathogenic role.2,3 In addition, sublingual immunotherapy (SLIT) is being increasingly used for the treatment of allergic rhinitis and allergic asthma. In this report, we describe a 9-year-old enteral feeding tube–dependent boy who developed increased esophageal eosinophilia, suggesting EoE after initiating aeroallergen SLIT.
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