Τρίτη 12 Ιουλίου 2016

Ictal time-irreversible intracranial EEG signals as markers of the epileptogenic zone

The aim of pre-surgical evaluation of patients suffering from pharmacoresistant epilepsies is to delineate the epileptogenic zone, which has been defined as the minimal area of cortex that must be resected to produce seizure-freedom (Luders et al., 2006). Since there is still no unique diagnostic method to precisely, directly and unequivocally identify the epileptogenic zone, it is crucial to extract as much information as possible from existing modalities. Intracranial EEG (iEEG) is currently the technology with the highest spatiotemporal resolution and the best signal-to-noise ratio to record the electric brain activity during human epileptic seizures.

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