Τρίτη 21 Ιουνίου 2016

A case of erythrema multiforme developing after H1N1 virus vaccine

2016-06-21T06-15-39Z
Source: Case Study and Case Report
Haydar Ucak, Demet Cicek, Savas Ozturk.
A 12-year-old male patient presented at our hospital complaining from eruptions that occurred 7 days after being inoculated with a single-dose monovalent H1N1 virus vaccine. Dermatological examination of the patient showed papules and occasional targetoid plaques particularly in the acral areas. The patient who did not have mucosal involvement did not have an infection or history of drug use in the last one month. Laboratory examinations did not reveal any pathology.Although its pathophysiology has not been fully understood yet, erythema multiforme is described as keratinocyte damage caused by the cell-mediated immune response to an antigenic stimulus. Infections play the major role in the etiology of erythema multiforme, but drugs, malignancies and vaccines, though rarely, are also held responsible. We are presenting the second literature case of EM that occurred secondary to monovalent influenza A/H1N1 vaccine.


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