Τρίτη 17 Μαΐου 2016

RNA modifications: what have we learned and where are we headed?

Nature Reviews Genetics 17, 365 (2016). doi:10.1038/nrg.2016.47

Authors: Michaela Frye, Samie R. Jaffrey, Tao Pan, Gideon Rechavi & Tsutomu Suzuki

Proper control of the transcriptome is key for diverse aspects of gene expression, cellular functions and development, and its disruption can result in disease. A rapidly accumulating wealth of studies are identifying and functionally characterizing diverse types of RNA base modifications in protein-coding and non-coding



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