Τρίτη 17 Μαΐου 2016

Gene regulation: Finding genetic target sites

Nature Reviews Genetics 17, 314 (2016). doi:10.1038/nrg.2016.53

Author: Darren J. Burgess

There is increasing realization that genetic variation in non-coding regulatory elements, such as enhancers, has a major role in evolution, complex traits and diseases. However, a key challenge is to identify the genes regulated by these elements in order to dissect the gene regulatory networks



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