Κυριακή 1 Νοεμβρίου 2020

HFUS Imaging of the Cochlea: A Feasibility Study for Anatomical Identification by Registration with MicroCT.

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HFUS Imaging of the Cochlea: A Feasibility Study for Anatomical Identification by Registration with MicroCT.

Ann Biomed Eng. 2020 Oct 30;:

Authors: Lavenir L, Zemiti N, Akkari M, Subsol G, Venail F, Poignet P

Abstract
Cochlear implantation consists in electrically stimulating the auditory nerve by inserting an electrode array inside the cochlea, a bony structure of the inner ear. In the absence of any visual feedback, the insertion results in many cases of damages of the internal structures. This paper presents a feasibility study on intraoperative imaging and identification of cochlear structures with high-frequency ultrasound (HFUS). 6 ex-vivo guinea pig cochleae were subjected to both US and microcomputed tomography (µCT) we respectively referred as intraoperative and preoperative modalities. For each sample, registration based on simulating US from the scanner was performed to allow a precise matching between the visible structures. According to two otologists, the procedure led to a target registration error of 0.32 mm ± 0.05. Thanks to referring to a better preoperative anatomical representation, we were able to intraoperatively identify the modiolus, both scalae vestibuli and tympani and deduce the location of the basilar membrane, all of which is of great interest for cochlear implantation. Our main objective is to extend this procedure to the human case and thus provide a new tool for inner ear surgery.

PMID: 33128180 [PubMed - as supplied by publisher]

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