AMEDEO Otorhinolaryngologyhttp://www.amedeo.comhttp://m.amedeo.com2019-10-07Your Personal Amedeo Web PageComputer: http://amedeo.com/summary/px.php?table=orl&cid=386453+Smartphone: http://m.amedeo.com/p12.php?table=orl&cid=3864532. http://OLIENA.comLanguage recovery after stroke3. http://TheWordBrain.comA short guide to fast language learning4. http://FJ4D.com + http://FB4D.com5087 Free Journals + 364 Selected Free BooksBest regards,Bernd Sebastian Kampshttp://linkedin.com/in/bskamps________________...
Sun Oct 06, 2019 13:15
Medicine by Alexandros G. SfakianakisCorrelation of tumor burden in sentinel lymph nodes with tumor burden in non-sentinel lymph nodes and survival in cutaneous melanoma.Correlation of tumor burden in sentinel lymph nodes with tumor burden in non-sentinel lymph nodes and survival in cutaneous melanoma.: CONCLUSIONS: In patients with CM who undergo CLND, SLN tumor burden predicts non-SLN tumor burden. SLN tumor burden parameters provide accurate prognostic stratification independent of non-SLN status...
Sun Oct 06, 2019 13:13
Nutrients, Vol. 11, Pages 2389: The Efficacy of Administering Fruit-Derived Polyphenols to Improve Health Biomarkers, Exercise Performance and Related Physiological ResponsesNutrients, Vol. 11, Pages 2389: The Efficacy of Administering Fruit-Derived Polyphenols to Improve Health Biomarkers, Exercise Performance and Related Physiological Responses Nutrients doi: 10.3390/nu11102389 Authors: Daniel S. Kashi Akbar Shabir Mariasole Da Boit Stephen J. Bailey Matthew F. Higgins Polyphenols are secondary...
08:19
International Journal of Molecular SciencesIJMS, Vol. 20, Pages 4942: L-Alanine Exporter, AlaE, of Escherichia coli Functions as a Safety Valve to Enhance Survival under Feast ConditionsIJMS, Vol. 20, Pages 4942: L-Alanine Exporter, AlaE, of Escherichia coli Functions as a Safety Valve to Enhance Survival under Feast Conditions International Journal of Molecular Sciences doi: 10.3390/ijms20194942 Authors: Satoshi Katsube Tasuke Ando Hiroshi Yoneyama The intracellular level of amino acids is determined...
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Antibiotics, Vol. 8, Pages 177: The Knowledge, Attitudes, and Practices of Community Pharmacists in their Approach to Antibiotic Use: A Nationwide Survey in ItalyAntibiotics, Vol. 8, Pages 177: The Knowledge, Attitudes, and Practices of Community Pharmacists in their Approach to Antibiotic Use: A Nationwide Survey in Italy Antibiotics doi: 10.3390/antibiotics8040177 Authors: Francesco Napolitano Giorgia Della Polla Caterina De Simone Chiara Lambiase Concetta Paola Pelullo Italo Francesco Angelillo...
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Adding RNA-Seq, Ambry Genetics Expects to Reduce VUS Results in Hereditary Cancer TestsPublished on Oct 04, 2019 nRichDx Targets Liquid Biopsy Space With Magnetic Sample Prep PlatformPublished on Oct 04, 2019 Canopy Biosciences Using Zellkraftwerk Buy to Move Into Protein AnalysisPublished on Oct 03, 2019 Blueprint Genetics to Open North American Lab as Biopharma Business GrowsPublished on Oct 03, 2019Laboratory Validation of a Kit-Based Liquid Biopsy NGS AssayPeter Mac's Andrew Fellowes will provide...
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Gene activation in human cells using CRISPR/Cpf1-p300 and CRISPR/Cpf1-SunTag systemsIn the original publication the Supplementary Material and Fig. 2 are incorrect. The correct version is provided in this correction article. The text HBG2 appearing in the article should be read as HBG1.Crystal structure and function of Rbj: A constitutively GTP-bound small G protein with an extra DnaJ domainShitsan Pai: the establishment of the first biophysics department in the worldInhibition of Rac1-dependent...
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Meta-Analysis of Placebo Response in Adult Antidepressant TrialsAbstractBackgroundRoughly 80% of the symptom improvement experienced on antidepressants in clinical trials is also observed in the placebo comparison group. Understanding the correlates of placebo improvement and response is important to designing efficient and successful trials of future antidepressants.ObjectiveThe objective of this meta-analysis was to investigate the magnitude of placebo symptom improvement and placebo response rates...
08:15
A Well-Aged MindMaintaining Your Cognitive Health,Your brain and body start slowing down as you age. But taking steps to maintain your cognitive health can help improve your overall well-being.Family Health MattersHow Twin Studies Can Help EveryoneTwins are similar in ways you can't see, too. That makes them a powerful tool for studying health and disease.Millions Taking Aspirin Without Clear BenefitEye Safety Tips for KidsVolunteers Needed for Study of Flu Vaccine and Heart DiseaseCancer Information...
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Clinical Otolaryngology, Early View, ORIGINAL ARTICLESRadioresistant laryngeal cancers upregulate...
Clinical Otolaryngology,Early View,ORIGINAL ARTICLESRadioresistant laryngeal cancers upregulate type 1 IGF receptor and exhibit increased cellular dependence on IGF and EGF signallingAli Qureishi, Guillaume Rieunier, Ketan A. Shah, Tamara Aleksic, Stuart C. Winter, Henrik Møller, Valentine M. MacaulayVersion of Record online: 04 October 2019ORIGINAL ARTICLESVoice burden in teachers and non‐teachers in a UK population: A questionnaire‐based surveyChaitanya Gadepalli MD, FRCS(ORL-HNS), Catherine Fullwood, Frances...
08:14
Clinical Otolaryngology,Accepted Articles,EDITORIAL COMMENTSUnderstanding and clinical relevance of chronic rhinosinusitis endotypesQasim Husain, Ahmad R. SedaghatFirst Published: 03 October 2019 Open AccessORIGINAL ARTICLESHealthcare utilization, follow‐up of guidelines and practice variation on rhinosinusitis in adults; a health care reimbursement claims study in the NetherlandsN.M. Kaper, M.C.J. Aarts, R.J. Stokroos, GJMG van der HeijdenFirst Published: 03 October 2019ORIGINAL ARTICLESPrognostic...
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Simulations at Work —a Framework for Configuring Simulation Fidelity with Training ObjectivesAbstractThis study aims to provide framework for considering fidelity in the design of simulator training. Simulator fidelity is often characterised as the level of physical and visual similarity with real work settings, and the importance of simulator fidelity in the creation of learning activities has been extensively debated. Based on a selected literature review and fieldwork on ship simulator training,...
08:13
Oral Human Papillomavirus Infection and Head and Neck Squamous Cell Carcinoma in Rural Northwest Cameroon by Eleni M. Rettig, Zhen Gooi, Richard Bardin, Mesele Bogale, Lisa Rooper, Everistus Acha, Wayne M. KochEndoscopic Inside-Out Mastoidectomy with the Ultrasonic Bone Aspirator by Rahul Mehta, Gauri Mankekar, Erica Mayland, Katie Melder, Moises A. Arriaga
08:12
Oxygen-Sensing Trio Wins NobelPublished on Oct 07, 2019Three researchers have won this year's Nobel Prize in Medicine or Physiology for their work uncovering how cells react to changing oxygen levels. Read more >Returning More and MorePublished on Oct 07, 2019The Wall Street Journal reports that some sequencing projects that currently return no or limited testing results are looking to expand what they tell participants. Read more >To the SourcePublished on Oct 07, 2019DNA testing traces Dutch...
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Clinicopathological evaluation of PD-L1 expression and cytotoxic T-lymphocyte infiltrates across intracranial molecular subgroups of ependymomas: are these tumors potential candidates for immune check-point blockade?AbstractImmune check-point blockade (ICB) targeting programmed cell death ligand-1 (PD-L1)/programmed death-1 (PD-1) axis has created paradigm shift in cancer treatment. 'ST-RELA' and 'PF-A' molecular subgroups of ependymomas (EPN) show poor outcomes. We aimed to understand the potential...
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Test yourself: question and answer question: painful knee swellingTest yourself answer: painful knee swellingBrowser's notesDiagnostic accuracy of imaging modalities in the detection of clinically diagnosed de Quervain's syndrome: a systematic reviewAbstractObjectivesTo collate and synthesise the literature to provide estimates of the diagnostic accuracy of imaging modalities, and summarise the reported imaging findings associated with de Quervain's syndrome.Materials and methodsA systematic search...
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48 ώρες στη Λακωνική Μάνη Πατήστε εδώ24 ώρες στο Notting HillΦθιώτιδα: Η άλλη πλευρά του ΠαρνασσούΠατήστε εδώΠατήστε εδώΚοπεγχάγη: Η πιο cool πρωτεύουσαΠατήστε εδώ
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,Breast Cancer Screening in High-Risk Men: A 12-Year Longitudinal Observational Study of Male Breast Imaging Utilization and Outcomes Selective mammography screening in men at elevated risk for breast cancer is beneficial and depicts clinically occult malignancy at a cancer detection rate higher than that of screening among women with average risk. Yiming Gao, Julia E. Goldberg...Samantha L. HellerBI-RADS, C-RADS, CAD-RADS, LI-RADS, Lung-RADS, NI-RADS, O-RADS, PI-RADS, TI-RADS: Reporting and Data...
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Diagnosing and treating COPD in the prehospital settingBy The MCHD Paramedic PodcastDistinguishing between COPD and comorbidities, and scaling treatment and pharmacology to disease progressionLoving an EMS provider with PTSDBy The Code Green CampaignA first responder's partner shares what it's like to stay strong from the sidelines, waiting for their loved one to ask for helpOTHER HIGHLIGHTS3 bad players in EMS airway managementBy Catherine R. CountsDr. Dan Spaite shares how to avoid the potential...
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Journal of Cutaneous Pathology,Accepted Articles,REVIEWSA concise review of Angiofibroma of Soft Tissue: a rare newly‐described entity that can be encountered by dermatopathologistsAndres E. Mindiola‐Romero MD, Nolan Maloney MD, Julia A. Bridge MD, Penelope Korkolopoulou MD, Stratigoula Sakellariou MD, Konstantinos Linos MDFirst Published: 30 September 2019CASE REPORTSDistinguishing bowenoid papulosis from Bowen disease in the mouth: a case reportJean Carlos Barbosa Ferreira DDS, MS, Henrique Moura...
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Lung Cancer Studies From TRACERx Consortium Explore How Tumor Cells EvolvePublished on Oct 07, 2019 Appeals Court Upholds Unpatentability of 23andMe IPPublished on Oct 07, 2019 Prostate Cancer Methylation Levels Linked to Regulatory Variants in GermlinePublished on Oct 07, 2019Featured in Depth nRichDx Targets Liquid Biopsy Space With Magnetic Sample Prep PlatformPublished on Oct 04, 2019 Adding RNA-Seq, Ambry Genetics Expects to Reduce VUS Results in Hereditary Cancer TestsPublished on Oct 04,...
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Otolaryngology–Head and Neck Surgery ,Original ResearchEffects of OSA Surgery on Leptin and Metabolic ProfilesChien-Hung Chin, Pei-Wen Lin, Hsin-Ching Lin, Michael Friedman, Meng-Chih LinOtolaryngology–Head and Neck SurgeryOct 1, 2019 | OnlineFirstOriginal ResearchSurgical Explantation of Bone-Anchored Hearing Devices: A 10-year Single Institution ReviewChristian G. Fritz, Dennis I. Bojrab, II, Kenny F. Lin, Christopher A. Schutt, Seilesh C. Babu, Robert S. HongOtolaryngology–Head and Neck SurgeryOct...
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Ear, Nose & Throat Journal , Rhinoscopic ClinicA Foreign Body in the Ostium of the Maxillary SinusJae Hoon LeeEar, Nose & Throat JournalOct 3, 2019 | OnlineFirstCase SeriesImplication and Management of Incidental Oropharyngeal Papillomas—A Retrospective Case Series ReviewDaniel Kim, Justin Siegel, Robert J. Chouake, Jan Geliebter, Craig H. ZalvanEar, Nose & Throat JournalOct 3, 2019 | OnlineFirstOstoscopic ClinicMoth in the Left EarChing-Ching Chiu, Yun-Ying SheEar, Nose & Throat...
08:06
Acute Flaccid Myelitis in the United States: 2015–2017,Tracy Ayers, Adriana Lopez, Adria Lee, Anita Kambhampati, W. Allan Nix, Elizabeth Henderson, Shannon Rogers, William C. Weldon, M. Steven Oberste, James Sejvar, Sarah E. Hopkins, Mark A. Pallansch, Janell A. Routh and Manisha PatelCommentaryAcute Flaccid Myelitis Surveillance: A Signal Through the NoiseKevin Messacar, Mark J. Abzug and Samuel R. Dominguez
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Waste in the US Health Care System: Estimated Costs and Potential for SavingsWilliam H. Shrank, MD, MSHS; Teresa L. Rogstad, MPH; Natasha Parekh, MD, MSEditorial: Waste in the US Health Care System; Howard Bauchner, MD; Phil B. Fontanarosa, MD, MBAEditorial: Elusive Waste—The Fermi Paradox in US Health Care; Donald M. Berwick, MD, MPPEditorial: Toward Evidence-Based Policy Making to Reduce Wasteful Health Care Spending ; Karen E. Joynt Maddox, MD, MPH; Mark B. McClellan, MD, PhDEditorial: Eliminating...
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Dermatologic TherapyAccepted ArticlesAccepted, unedited articles published online and citable. The final edited and typeset Version of Record will appear in the future.ORIGINAL PAPERSThe 24‐hour, 28‐day and 7‐day post moisturizing efficacy of ceramides 1, 3, 6‐II containing moisturizing cream compared with hydrophilic cream on skin dryness and barrier disruption in senile xerosis treatmentDr. Piyanuch Tragulplaingam M.D., Dr. Supanee Sugkraroek M.D., Assistant Professor Therdpong Tempark M.D.e13090...
08:04
Impact of depressive symptoms on worklife expectancy: a longitudinal study on Danish employeesJacob Pedersen, Sannie Vester Thorsen, Malene Friis Andersen et al. (2019-10-03)10.1136/oemed-2019-105961
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Rapid eye movement sleep and neuronal developmentPurpose of review To understand the importance of rapid eye movement (REM) sleep in the cognitive and sensorimotor development via neural plasticity during embryonic development and infants. Recent findings REM sleep has remained a mystery as many of the underlying mechanisms of REM sleep remain unclear. Recent findings have demonstrated that REM sleep selectively prunes newly formed dendritic spines in the developing brain as well as strengthening...
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Skin autofluorescence: an emerging biomarker in persons with kidney diseasePurpose of review Skin autofluorescence (SAF) is a measure of the accumulation of advanced glycation end-products (AGEs) proposed to act as a marker of 'cumulative metabolic stress'. This article discusses mechanisms of AGE formation and reviews published literature on SAF as a biomarker and risk factor across the spectrum of kidney disease. Recent findings SAF is elevated in adults and children on dialysis. Higher SAF is...
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Drug causes of intracerebral haemorrhage,Summary Many drugs have the potential to cause intracerebral haemorrhage. The mechanisms that underlie this association include elevation of blood pressure and increasing bleeding tendency. The consequences of intracerebral haemorrhage can be devastating for the individual, so careful risk assessment prior to drug initiation and close monitoring during treatment should be enacted when using medicines with an established association with haemorrhagic stroke.
08:02
Esophageal Leukoplakia , Hernandez, Patricia V. MD1; Snyder, Diana MD1; Kahn, Allon MD1; Wang, Kenneth K. MD2; Katzka, David A. MD2; Horsley-Silva, Jennifer L. MD1ACG Case Reports Journal: September 2019 - Volume 6 - Issue 9 - p e00213doi: 10.14309/crj.0000000000000213CASE REPORTA 64-year-old white man with a history of tobacco use and stable weight presented to the gastroenterology clinic due to an 11-month history of solid-food esophageal dysphagia. On physical examination, patient was alert and...
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Ascariasis Causing Biliary ColicNo abstract availableAcrodermatitis Enteropathica Associated With Inflammatory Bowel DiseaseNo abstract availableCholecystectomy Clip Migration and RetrievalNo abstract availableObstructive Jaundice Is Not Always Surgical!A 60-year-old diabetic man presented with a 1-month history of obstructive jaundice, weight loss of 16 kg, and fever and chills for more than 7 days. On examination, the patient was found to have deep icterus, tenderness in the right hypochondrium,...
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OncologyEducation ,To view, click on the images below.______________________________________________________________
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Table of ContentsCONTRIBUTORSEDITOR'S PREFACEREVIEW ARTICLESSELF-ASSESSMENT AND CMELIST OF ABBREVIATIONSKEY POINTS FOR ISSUEISSUE OVERVIEWREVIEW ARTICLESThe PupilBouffard, Marc A. Ischemic Optic NeuropathyMorrow, Mark J. Optic NeuritisBennett, Jeffrey L. Toxic-Metabolic and Hereditary Optic NeuropathiesOliveira, Cristiano Idiopathic Intracranial HypertensionThurtell, Matthew J. Chiasmal and Postchiasmal DiseaseMoss, Heather E. Higher Cortical Visual DisordersPrasad, Sashank; Dinkin, Marc Approach...
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High mobility group box protein 1 neutralization therapy in ovine bacteremia: Lessons learned from an ovine septic shock model incorporating intensive care supportNatalie E. Stevens, Coralie H. Nash, Cara K. Fraser, Tim R. Kuchel, Matthew J. Maiden, Marianne J. Chapman, Kerrilyn R. Diener, John D. HayballView Abstract ❯PKCδ promotes fertilization of mouse embryos in early development via the Cdc25B signaling pathwayYanchun Liu, Xin Deng, Didi Wu, Minglin Jin, Bingzhi YuView Abstract ❯Identification...
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Me2SO- and serum-free cryopreservation of human umbilical cord mesenchymal stem cells using electroporation-assisted delivery of sugarsPublication date: Available online 5 October 2019Source: CryobiologyAuthor(s): Vitalii Mutsenko, Ariana Barlič, Tamara Pezić, Janja Dermol-Černe, Barbara Dovgan, Bulat Sydykov, Willem F. Wolkers, Igor I. Katkov, Birgit Glasmacher, Damijan Miklavčič, Oleksandr GryshkovAbstractCryopreservation is the universal technology used to enable long-term storage and continuous...
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A predatory worldNo abstract availableHow to avoid predatory and hijacking publishers?No abstract availableThe challenge of the predatory open-access publishing outbreakNo abstract availableAllogeneic red cell transfusion and its influence on relevant humoral and cellular immunological parameters: A prospective observational trialBACKGROUND It is assumed that transfusion of allogeneic red cells is associated with increased peri-operative mortality and morbidity. Also assumed is the theory of transfusion-related...
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Diurnal variation of inflammatory plasma proteins involved in painIntroduction: Proteomics is a powerful approach for biochemical research because it directly studies the main functional components of biochemical systems. The understanding of the normal fluctuations of the proteome in health is essential to identify pain-specific biomarkers. Objective: To investigate fluctuations of the plasma proteome in healthy pain-free individuals. Methods: Blood samples were structurally collected in the early...
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Evaluation of the Association of Early Elevated Lactate With Outcomes in Children With Severe Sepsis or Septic ShockObjective The aim of the study was to assess the association of initial lactate (L0) with mortality in children with severe sepsis. Methods This prospective cohort study included 74 patients younger than 18 years with severe sepsis admitted to the pediatric intensive care unit (PICU) of a tertiary, academic children's hospital with lactate measured within 3 hours of meeting severe sepsis...
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Neuro-arrhythmology: a challenging field of action and research: a review from the Task Force of Neuro-arrhythmology of Italian Association of Arrhythmias and Cardiac PacingThere is a growing interest in the study of the mechanisms of heart and brain interactions with the aim to improve the management of high-impact cardiac rhythm disorders, first of all atrial fibrillation. However, there are several topics to which the scientific interests of cardiologists and neurologists converge constituting...
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Surgical Care Improvement Program and surgical site infections: initiatives to improve outcome in patients with joint replacements in a tertiary care center in PakistanIntroduction: The Surgical Care Improvement Programme (SCIP) was initiated in 2002 with the vision of reducing the morbidity and mortality associated with postoperative surgical site infection by addresses to the antibiotics use and early discontinuation, catheter removal within 48 hours postoperatively, use of clipper for hair removal,...
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Antibody-mediated control of HIV-1 infection through an alternative pathwayNo abstract availableThe antagonism of folate receptor by dolutegravir: developmental toxicity reduction by supplemental folic acidObjective: Maternal folate (vitamin B9) status is the largest known modifier of neural tube defect risk, so we evaluated folate-related mechanisms of action for dolutegravir (DTG) developmental toxicity. Design: Folate receptor 1 (FOLR1) was examined as a target for DTG developmental toxicity using...
07:51
Turning Intention Into Participation in Occupational Health Promotion Courses? The Moderating Role of Organizational, Intrapersonal, and Interpersonal FactorsObjective: Investigate organizational, intrapersonal (expectations, risk, strain, self-care), and interpersonal (health-oriented leadership) factors as predictors for employees' participation in occupational health promotion (OHP) and the mediating effect of intention. Identifying moderators that strengthen the relationship between intention...
07:50
Tailoring Individualized Evaluation of Pediatric Abdominal Pain Using Ecological Momentary Assessment (EMA): A Pilot Study Testing Feasibility and AcceptabilityObjective: The current study aimed to determine if it was feasible and acceptable to use ecological momentary assessment to assess individual associations between biopsychosocial contributors to chronic abdominal pain with 2 objective sensors and a mobile application. Specifically, we aimed to determine if it was possible to identify individualized...
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Editorial: Can we end HIV as a public health problem globally? Progress towards achieving the UNAIDS 90–90–90 goalsNo abstract availableReaching 90–90–90 in BotswanaPurpose of review Botswana, a small country in southern Africa, has had a very high prevalence of HIV since about 1995. It seems important to analyze the response of this country to help us understand how it became one of the first nations to achieve the 90–90–90 targets. Recent findings Botswana began a national program for treatment...
07:49
Myocardial Injury After Noncardiac Surgery: A Systematic Review and Meta-AnalysisMyocardial injury after noncardiac surgery (MINS) is a common postoperative complication associated with adverse cardiovascular outcomes. The purpose of this systematic review was to determine the incidence, clinical features, pathogenesis, management, and outcomes of MINS. We searched PubMed, Embase, Central and Web of Science databases for studies reporting the incidence, clinical features, and prognosis of MINS. Data...
07:49
Nutrients, Vol. 11, Pages 2389: The Efficacy of A...
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