International Journal of Environmental Research and Public Health IJERPH, Vol. 16, Pages 2874: "Everyone Has the Right to Drink Beer": A Stakeholder Analysis of Challenges to Youth Alcohol Harm-Reduction Policies in LebanonIJERPH, Vol. 16, Pages 2874: "Everyone Has the Right to Drink Beer": A Stakeholder Analysis of Challenges to Youth Alcohol Harm-Reduction Policies in Lebanon International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16162874 Authors: Rima T Nakkash Lilian...
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ScienceDirect Publication: American Journal of Infection Control Instillation of disinfectant behind a temporary obstruction created by an inflated urinary catheter balloon improves sink drain disinfectionPublication date: Available online 8 August 2019Source: American Journal of Infection ControlAuthor(s): Lucas D. Jones, Thriveen S.C. Mana, Jennifer L. Cadnum, Annette L. Jencson, Heba Alhmidi, Sandra Y. Silva, Brigid M. Wilson, Curtis J. DonskeyScienceDirect Publication: American Journal of...
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pubmed: "clin exp otorhinola... Neutrophils as a Protagonist and Target in Chronic Rhinosinusitis.Related ArticlesNeutrophils as a Protagonist and Target in Chronic Rhinosinusitis. Clin Exp Otorhinolaryngol. 2019 Aug 10;: Authors: Wang H, Pan L, Liu Z Abstract Neutrophils have traditionally been acknowledged as the first immune cells that are recruited to inflamed tissues during acute inflammation. By contrast, their importance in the context of chronic inflammation has been studied in less depth....
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pubmed: "front oncol"[jour] Flavonoid Derivative of Cannabis Demonstrates Therapeutic Potential in Preclinical Models of Metastatic Pancreatic Cancer.Related ArticlesFlavonoid Derivative of Cannabis Demonstrates Therapeutic Potential in Preclinical Models of Metastatic Pancreatic Cancer. Front Oncol. 2019;9:660 Authors: Moreau M, Ibeh U, Decosmo K, Bih N, Yasmin-Karim S, Toyang N, Lowe H, Ngwa W Abstract Pancreatic cancer is particularly refractory to modern therapies, with a 5-year survival rate...
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Laser Improvement in viability and mineralization of osteoporotic bone marrow mesenchymal stem cell through combined application of photobiomodulation therapy and oxytocinAbstract The probable positive effects of photobiomodulation therapy (PBMT) and oxytocin (OT) treatments together or alone were evaluated on cell viability along with the changes in the gene expression of Osteocalcin (OC), Osteoprotegerin (OPG), and Runt-related transcription factor 2 (Runx2) levels of sham (healthy)-Bone marrow...
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Current topics in medicinal chemistry A Review of PCSK9 Inhibitors and their effects on cardiovascular disease.Related ArticlesA Review of PCSK9 Inhibitors and their effects on cardiovascular disease. Curr Top Med Chem. 2019 Aug 08;: Authors: Chen B, Zhao P, Shi X, Cui Y, Hou A Abstract BACKGROUND: Cardiovascular disease remains the leading cause of morbidity and mortality in the world, with elevated low density lipoprotein-cholesterol (LDL-C) levels as a major risk factor. Lower levels of LDL-C...
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pubmed: cell cycle arrest DREAM and RB cooperate to induce gene repression and cell-cycle arrest in response to p53 activation.Related ArticlesDREAM and RB cooperate to induce gene repression and cell-cycle arrest in response to p53 activation. Nucleic Acids Res. 2019 Aug 10;: Authors: Uxa S, Bernhart SH, Mages CFS, Fischer M, Kohler R, Hoffmann S, Stadler PF, Engeland K, Müller GA Abstract Most human cancers acquire mutations causing defects in the p53 signaling pathway. The tumor suppressor p53...
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ScienceDirect Publication: Annals of Anatomy - Anatomischer Anzeiger Characterisation of flexor digitorum profundus, flexor digitorum superficialis and extensor digitorum communis by electrophoresis and immunohistochemical analysis of myosin heavy chain isoforms in older menPublication date: Available online 10 August 2019Source: Annals of Anatomy - Anatomischer AnzeigerAuthor(s): Marija Meznaric, Andrej ČarniAbstractIntroductionFew data exist on the fiber type composition of the extrinsic finger...
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J Clin Neurosci Corrigendum to "Spinal dural tenting sutures in intradural tumor surgery: A technical insight" [J Clin Neurosci 61 (2019) 322-323].Related ArticlesCorrigendum to "Spinal dural tenting sutures in intradural tumor surgery: A technical insight" [J Clin Neurosci 61 (2019) 322-323]. J Clin Neurosci. 2019 Aug 06;: Authors: Pesce A, Palmieri M, Frati A, Polli FM, Raco A PMID: 31399321 [PubMed - as supplied by publisher]J Clin Neurosci18hNeuroangiography patterns of the middle cerebral artery:...
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SAGE Publications Inc: Technology in Cancer Research & Treatment: Table of Contents Tumor-Treating Fields Induce RAW264.7 Macrophage Activation Via NK-κB/MAPK Signaling PathwaysTechnology in Cancer Research &Treatment, Volume 18, Issue , January 2019. Objective:Tumor-treating fields are currently used to successfully treat various cancers; however, the specific pathways associated with its efficacy remain unknown in the immune responses. Here, we evaluated tumor-treating fields–mediated...
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Head and Neck Pediatric Tracheal Surgery: A 25-year Review of Slide Tracheoplasty and Tracheal Resection.Related ArticlesPediatric Tracheal Surgery: A 25-year Review of Slide Tracheoplasty and Tracheal Resection. Ann Thorac Surg. 2019 Aug 07;: Authors: Stephens EH, Eltayeb O, Mongé MC, Forbess JM, Rastatter JC, Rigsby CK, Backer CL Abstract BACKGROUND: The purpose of this study was to assess the outcomes of slide tracheoplasty and tracheal resection in pediatric patients and analyze our data for...
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International journal of basic and clinical endocrinology Metformin in overweight and obese women with gestational diabetes: a propensity score-matched studyAbstract Purpose Obesity and gestational diabetes mellitus (GDM) have an independent negative impact in pregnancy outcomes. Excessive gestational weight gain (GWG) represents an additional high-risk condition for adverse outcomes. The aims of this study were to evaluate the potential effect of metformin in GWG in overweight or obese women with...
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Latest Results for Investigational New Drugs Germinal Immunogenetics predict treatment outcome for PD-1/PD-L1 checkpoint inhibitorsSummary Background Checkpoint inhibitors bring marked benefits but only in a minority of patients and may also be associated with severe adverse events. Treatment outcome still cannot be faithfully predicted. The following study hypothesized that host genetics could be applied as predictive biomarkers for checkpoint inhibitor response and immune-related adverse events....
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Oral and Maxillofacial SurgeryRisk Factors Associated with Malignant Transformation in Oral Leukoplakia Patients in a Chinese Population: A Retrospective StudyPublication date: Available online 9 August 2019Source: Journal of Oral and Maxillofacial SurgeryAuthor(s): Wenyan Wu, Zhen Wang, Zengtong ZhouAbstractPurposeThe study aim was to investigate the risk factors for the progress of oral leukoplakia (OLK) into malignancy.Patients and MethodsA total of 2628 OLK patients were retrospectively reviewed....
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Plastic, Reconstructive & Aesthetic SurgeryEfficacy of an external volume expansion device and autologous fat grafting for breast reconstruction following breast conserving surgery & total mastectomy: small improvements in quality of life found in a prospective cohort study.Although autologous fat grafting (AFG) for breast reconstruction is feasible, the best methods have yet to be established. This study aimed to assess the efficacy of fat grafting using an external expansion device for...
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The Journal of PhysiologyEvidence of adaptation of maternofetal transport of glutamine relative to placental size in normal mice, and in those with fetal growth restrictionKey points Fetal growth restriction (FGR) is a major risk factor for stillbirth and has significant impact upon lifelong health. A small, poorly functioning placenta, as evidenced by reduced transport of nutrients to the baby, underpins FGR. It remains unclear how a small but normal placenta differs from the small FGR placenta...
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Allergy and Clinical ImmunologySelective role of neurokinin B in IL-31–induced itch response in micePublication date: Available online 9 August 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Daiji Sakata, Takehito Uruno, Keisuke Matsubara, Tsugunobu Andoh, Kazuhiko Yamamura, Yuki Magoshi, Kazufumi Kunimura, Yasuhisa Kamikaseda, Masutaka Furue, Yoshinori FukuiAllergy and Clinical Immunology1dDedicator of cytokinesis protein 2 couples with lymphoid enhancer–binding factor 1 to regulate...
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Journal of Internal MedicineD‐dimer levels and risk of recurrence following provoked venous thromboembolism: Findings from the RIETE registryAbstract Background Patients with venous thromboembolism (VTE) secondary to transient risk factors may develop VTE recurrences after discontinuing anticoagulation. Identifying at‐risk patients could help to guide the duration of therapy. Methods We used the RIETE database to assess the prognostic value of d‐dimer testing after discontinuing anticoagulation...
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Journal of Cancer Research and Clinical Oncology Protective effect of the "food-microorganism-SCFAs" axis on colorectal cancer: from basic research to practical applicationAbstracts Background Recent studies have shown that the short-chain fatty acids (SCFAs) produced by the gut microbiota play a positive role in the development of colorectal cancer (CRC). Aims This study aims to elucidate the "food-microorganism-SCFAs" axis and to provide guidance for prevention and intervention in CRC. ...Journal...
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Gait & PostureMeasures of knee and gait function and radiographic severity of knee osteoarthritis – A cross-sectional studyPublication date: Available online 10 August 2019Source: Gait & PostureAuthor(s): J.E. Naili, E.W. Broström, B. Clausen, A. Holsgaard-LarsenGait & Posture18hINVESTIGATING THE EFFECT OF A PASSIVE EXOSKELETON ON THE ACTIVITY OF LOW BACK MUSCLES DURING DIFFERENT PHASES OF REPETITIVE DYNAMIC TASK.Publication date: Available online 9 August 2019Source: Gait & PostureAuthor(s):Gait...
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Clinical AnatomyIssue InformationClinical Anatomy1dMark above section as read ScienceDirect Publication: Pathology - Research and PracticeOver Expression of Amphiregulin Promoted Malignant Progression in Gastric CancerPublication date: Available online 10 August 2019Source: Pathology - Research and PracticeAuthor(s): Jiajia Jiang, Wei Zhao, Qi Tang, Bing Wang, Xiaohua Li, Zhenqing FengAbstractHuman Amphiregulin (AREG) was found to be over expressed in many types of cancer patients including gastric...
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The Angle orthodontist,http://www.angleorthodontist.org/Three-dimensional analysis of lip changes in response to simulated maxillary incisor advancement.Related ArticlesThree-dimensional analysis of lip changes in response to simulated maxillary incisor advancement. Angle Orthod. 2019 Aug 09;: Authors: Au J, Mei L, Bennani F, Kang A, Farella M Abstract OBJECTIVE: To assess the immediate response of lips in three dimensions (3D) resulting from simulated maxillary incisor advancement. MATERIALS AND...
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Journal of Neuroscience MethodsNew Software dedicated to Virtual Mazes for Human NeuroCognitive investigationsPublication date: Available online 10 August 2019Source: Journal of Neuroscience MethodsAuthor(s): M.L. Machado, N. Lefèvre, B. Philoxene, A. Le Gall, S. Madeleine, P. Fleury, P.F. Smith, S. BesnardAbstractBackgroundcompared to previous neuropsychological investigations with standard paper-pen tests limited to test complex spatial learning and memory processes, 3-D virtual immersive technology...
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Academic RadiologyAutomated Segmentation of Tissues Using CT and MRI: A Systematic ReviewPublication date: Available online 10 August 2019Source: Academic RadiologyAuthor(s): Leon Lenchik, Laura Heacock, Ashley A. Weaver, Robert D. Boutin, Tessa S. Cook, Jason Itri, Christopher G. Filippi, Rao P. Gullapalli, James Lee, Marianna Zagurovskaya, Tara Retson, Kendra Godwin, Joey Nicholson, Ponnada A. NarayanaRationale and ObjectivesThe automated segmentation of organs and tissues throughout the body...
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Journal of Communication Disorders (open access)Establishing consensus among community clinicians on how to categorize and define preschoolers' speech and language impairments at assessmentPublication date: Available online 10 August 2019Source: Journal of Communication DisordersAuthor(s): Barbara Jane Cunningham, Elaine Yeun Kwok, Lyn Turkstra, Janis Oram CardyAbstractPurposeTo achieve consensus amongst speech-language pathologists (SLPs) on the categories and definitions of preschoolers' communication...
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Experimental DermatologyThe non‐homogenous distribution and aggregation of carotenoids in the stratum corneum correlates with the organization of intercellular lipids in vivoAbstract The human stratum corneum (SC) contains an abundant amount of carotenoid antioxidants, quenching free radicals and thereby protecting the skin. For the precise measurements of the depth‐dependent carotenoid concentration, confocal Raman microscopy is a suitable method. The quantitative concentration can be determined...
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DiversityDiversity, Vol. 11, Pages 130: Immediate Effects of Hurricanes on a Diverse Coral/Mangrove Ecosystem in the U.S. Virgin Islands and the Potential for RecoveryDiversity, Vol. 11, Pages 130: Immediate Effects of Hurricanes on a Diverse Coral/Mangrove Ecosystem in the U.S. Virgin Islands and the Potential for Recovery Diversity doi: 10.3390/d11080130 Authors: Caroline S. Rogers Hurricanes Irma and Maria, two powerful storms that hit the U.S. Virgin Islands less than 2 weeks apart in September...
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Cerebral amyloidoma: A mimicker of granulomatous disease on brain MRIPublication date: September 2019Source: Journal of Neuroradiology, Volume 46, Issue 5Author(s): Alireza Radmanesh, Matthew D. Wood, Andrew W. BollenIntracranial aneurysms treatment with Barricade coils: Safety and 1-year efficacy in a prospective, single-center seriesPublication date: September 2019Source: Journal of Neuroradiology, Volume 46, Issue 5Author(s): Raoul Guerreiro-Simoes, Sébastien Soize, Matthias Gawlitza, Pierre-François...
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Extreme Risk Protection Orders: An Opportunity to Improve Gun Violence Prevention TrainingStates are increasingly enacting extreme risk protection order (ERPO) laws, also known as "red flag" or gun violence restraining order laws, as one part of a multidisciplinary approach to address the national gun violence epidemic. Passed into law in more than 10 states and under consideration by legislatures in approximately 30 others, ERPO laws create a legal process to temporarily remove firearms from people...
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Intracranial subarachnoid hemorrhage resulting from non-cervical spinal arteriovenous lesions: Analysis of possible cause of bleeding and literature reviewPublication date: September 2019Source: Clinical Neurology and Neurosurgery, Volume 184Author(s): He Yue, Wang Ling, Yibo Ou, Hanmin Chen, Zhang Po, Baofeng Wang, Jiasheng Yu, Dongsheng GuoAbstractSubarachnoid hemorrhage (SAH) or intraventricle hemorrhage (IVH) with negative cerebral digital subtraction angiography (DSA) results, which are due...
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Delayed graft function in simultaneous liver kidney transplantationBackground: Delayed graft function (DGF) is associated with inferior posttransplant outcomes in kidney transplantation. Given these adverse outcomes, we sought to determine the incidence, unique risk factors, and posttransplant outcomes for simultaneous liver kidney (SLK) transplant recipients developing DGF. Methods: We studied 6214 adult SLK recipients from March 2002 to February 2017 using the Scientific Registry of Transplant...
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Using Quantitative Computed Tomographic Imaging to Understand Chronic Obstructive Pulmonary Disease and Fibrotic Interstitial Lung Disease: State of the Art and Future DirectionsComputed tomography (CT) is commonly used in the evaluation and management of patients with diffuse lung pathologies, including chronic obstructive pulmonary disease (COPD) and fibrotic interstitial lung disease (ILD). In clinical practice, the qualitative (visual) assessment of CT images by a radiologist provides insight...
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Is the rule of halves still relevant today? A cross-sectional analysis of hypertension detection, treatment and control in an urban communityAims: To estimate percentages of patients with undiagnosed hypertension, diagnosed untreated hypertension and diagnosed, treated and uncontrolled hypertension and to identify sociodemographic factors for diagnosed, uncontrolled hypertension and not having a blood pressure (BP) reading recorded. Methods: Data from 320 094 patients aged 18 to less than 80 years...
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Trichotillomania (hair pulling disorder): Clinical characteristics, psychosocial aspects, treatment approaches, and ethical considerationsKatlein França, Anagha Kumar, David Castillo, Mohammad Jafferany, Marcelo Hyczy da Costa Neto, Katerina Damevska, Uwe Wollina, Torello Lottie12622 | First Published: 28 August 2018Aesthetic dermatology: What's new, what's true?Uwe Wollina, Piotr Brzezinskie12623 | First Published: 04 September 2018Travelers' tropical skin diseases: Challenges and interventionsPaulo...
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Substantial and Sustained Improvements in Blood Pressure, Weight and Lipid Profiles from a Carbohydrate Restricted Diet: An Observational Study of Insulin Resistant Patients in Primary CareDavid J. Unwin, Simon D. Tobin, Scott W. Murray, Christine Delon and Adrian J. BradyInt. J. Environ. Res. Public Health 2019, 16(15), 2680; doi:10.3390/ijerph16152680Featured PapersArticle: Workplace-Based Exercise Intervention Improves Work Ability in Office Workers: A Cluster Randomised Controlled TrialJoshua...
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Activated cytotoxic T cells within zoonotic cutaneous leishmaniasis lesionsThouraya Boussoffara, Mohamed Samir Boubaker, Melika Ben Ahmed, Mourad Mokni, Salma Feriani, Afif Ben Salah, Hechmi LouzirPages: 95-104 | First Published: 17 April 2019 The aim of this study is to investigate the role of cytotoxic cells on the outcome of the Zoonotic cutaneous leishmaniasis (ZCL) due to infection by Leishmania major. We demonstrated the presence of cytotoxic T lymphocytes expressing high levels of granzyme...
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Microbiomes: getting the big picture on microorganismsBacteria, fungi, viruses… we associate them with nasty health conditions and incurable diseases. However as part of greater microbiome environments, they can play a crucial role in keeping humans and our planet healthy.
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HEAD NECK 1.Head-neck rotational movements using DidRen laser test indicate children and seniors' lower performance Science.gov (United States)Pitance, Laurent; Brismée, Jean-Michel; Detrembleur, Christine; Dierick, Frédéric2019-07-25 PubMed CentralDOI: 10.1371/journal.pone.0219515 ISSN: 1932-6203 Volume: 14 Issue: 7Sensorimotor control strategies during cervical axial rotation movements have been previously explored in narrow age ranges but never concurrently in Children and Seniors during a...
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Neurological structures and mediators of pain sensation in anterior cruciate ligament reconstructionPublication date: September 2019Source: Annals of Anatomy - Anatomischer Anzeiger, Volume 225Author(s): Andrew J. Hong, Avinesh Agarwalla, Joseph N. Liu, Anirudh K. Gowd, Sean McMillan, Paul M. Sethi, Nirav H. AminAbstractAnterior cruciate ligament (ACL) tears is a devastating injury and one of the most common knee injuries experienced by athletes in the United States. Although patients reach maximal...
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Ultrasound-derived Biceps Femoris Long-Head Fascicle Length: Extrapolation PitfallsPurpose To compare biceps femoris long-head (BFlh) fascicle lengths (Lfs) obtained with different ultrasound-based approaches: 1) single ultrasound images and linear Lf extrapolation; 2) single ultrasound images and one of two different trigonometric equations (termed equations A and B); and 3) extended field of view (EFOV) ultrasound images. Methods Thirty-seven elite alpine skiers (21.7±2.8 yrs) without a previous...
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Cell death in photodynamic therapy: From oxidative stress to anti-tumor immunityPublication date: Available online 8 August 2019Source: Biochimica et Biophysica Acta (BBA) - Reviews on CancerAuthor(s): Claire Donohoe, Mathias O. Senge, Luís G. Arnaut, Lígia C. Gomes-da-SilvaAbstractPhotodynamic therapy is a promising approach for cancer treatment that relies on the administration of a photosensitizer followed by tumor illumination. The generated oxidative stress may activate multiple mechanism of...
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OncologyEducation is proud to present our Best of ASCO Vancouver 2019 Presentations.These videos incorporate perspectives from our faculty of experts.Please enjoy and share with your colleagues.To view the videos, click the images below:
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Nurses' Education, Confidence, and Competence in Appropriate Dressing ChoiceBACKGROUND Wound assessment and treatment are essential aspects of nursing care. Dressing-associated complications can delay wound healing, causing unnecessary patient distress. Despite evidence suggesting that dressings should be changed infrequently, there still remains a tendency for healthcare professionals to remove dressings regularly, increasing the risk of complications and the cost of wound care. OBJECTIVE To understand...
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Targeted Drug Erdafitinib Benefits Some Patients with Advanced Bladder Cancer08/09/2019New clinical trial findings confirm that the targeted therapy erdafitinib (Balversa) can benefit patients with advanced bladder cancer whose tumors have a genetic alteration in one of the four FGFR genes.
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Circadian Expression of Genes Disrupted in Brains of Individuals With SchizophreniaPublished on Aug 09, 2019 Quanterix Prices Public Offering of Stock, Expects $60M in ProceedsPublished on Aug 09, 2019 Quidel Q2 Revenues Up 5 Percent on Rapid Immunoassay BusinessPublished on Aug 08, 2019 NantHealth Q2 Revenues Grow 17 PercentPublished on Aug 08, 2019 Bionano Genomics Q2 Revenues Fall 36 PercentPublished on Aug 08, 2019 Selection Signals Uncovered In African Rainforest Hunter-Gatherer ExomesPublished...
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Is immunotherapy with fungal vaccines effective?Purpose of review Although allergen immunotherapy (AIT) for fungi has been performed for many years, evidence clearly demonstrating its clinical benefit are still lacking. Here, we reviewed the available studies assessing efficacy and safety of AIT for molds. Recent findings Studies on AIT for fungi were performed only for the two predominating mold species in the external environment, namely Cladosporium and Alternaria. There is no evidence for other...
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Development and Evaluation of a Quick Response Code–Based Nursing Education Program for Operating and Recovery Room NursesThe purpose of this study was to develop and evaluate the effectiveness of a quick response code–based nursing education program to improve the competence of operation and recovery room nurses. An experimental methodological design was used to develop a quick response code–based nursing educational program and analyze its effects and nurses' satisfaction with its use. The quick...
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National Trends in Timing of Death Among Patients With Septic Shock, 1994–2014Objectives: To assess trends in timing of mortality among patients with septic shock. Design: Retrospective cohort study. Setting: Agency for Healthcare Research and Quality's Healthcare Cost and Utilization Project's National Inpatient Sample, 1994–2014. Patients: Hospitalized adults (≥ 18 yr) with International Classification of Diseases, 9th Edition, Clinical Modification codes consistent with septic shock; secondary...
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Do men and women arrive, stay, and respond differently to cognitive behavior group therapy for social anxiety disorder?" [J. Anxiety Disord. 64 (May) (2019) 64–70]Publication date: Available online 10 August 2019Source: Journal of Anxiety DisordersAuthor(s): Maya Asher, Haggai Hermesh, Shay Gur, Sofi Marom, Idan M. AderkaAttentional bias and its temporal dynamics among war veterans suffering from chronic pain: Investigating the contribution of post-traumatic stress symptomsPublication date: August...
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Upper Airway Collapsibility during Dexmedetomidine and Propofol Sedation in Healthy Volunteers: A Nonblinded Randomized Crossover StudyÅse Lodenius, M.D., Ph.D., D.E.S.A.; Kathleen J. Maddison, Ph.D.; Brad K. Lawther, M.D.; Mika Scheinin, M.D., Ph.D.; Lars I. Eriksson, M.D., Ph.D., F.R.C.A.; et al Peter R. Eastwood, Ph.D.; David R. Hillman, M.B.B.S.; Malin Jonsson Fagerlund, M.D., Ph.D., D.E.S.A.; Jennifer H. Walsh, M.Sc., Ph.D Author NotesFrom the Function Perioperative Medicine and Intensive Care,...
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Intraoperative Mechanical Ventilation and Postoperative Pulmonary Complications after Cardiac SurgeryMichael R. Mathis, M.D.; Neal M. Duggal, M.D.; Donald S. Likosky, Ph.D.; Jonathan W. Haft, M.D.; Nicholas J. Douville, M.D., Ph.D.; et al Michelle T. Vaughn, M.P.H.; Michael D. Maile, M.D., M.S.; Randal S. Blank, M.D., Ph.D.; Douglas A. Colquhoun, M.B., Ch.B., M.Sc., M.P.H.; Raymond J. Strobel, M.D., M.S.; Allison M. Janda, M.D.; Min Zhang, Ph.D.; Sachin Kheterpal, M.D., M.B.A.; Milo C. Engoren, M.D. Author...
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Perioperative laboratory monitoring in congenital haemophilia patients with inhibitors: a systematic literature reviewAlthough the use of clotting factor concentrates is the mainstay of haemophilia care, the development of inhibitors complicates disease management. Perioperative management of patients with inhibitors is therefore a challenge. A systematic literature review was performed to identify literature reporting on the perioperative monitoring and management of haemophilia. MEDLINE, Embase...
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Perioperative Medicine Upper Airway Collapsibility during Dexmedetomidine and Propofol Sedation in Healthy Volunteers: A Nonblinded Randomized Crossover StudyÅse Lodenius, M.D., Ph.D., D.E.S.A.; Kathleen J. Maddison, Ph.D.; Brad K. Lawther, M.D.; Mika Scheinin, M.D., Ph.D.; Lars I. Eriksson, M.D., Ph.D., F.R.C.A.; Peter R. Eastwood, Ph.D.; David R. Hillman, M.B.B.S.; Malin Jonsson Fagerlund, M.D., Ph.D., D.E.S.A.; Jennifer H. Walsh, M.Sc., Ph.DAnesthesiology Published online August 08, 2019. doi:10.1097/ALN.0000000000002883Intraoperative...
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Candidate Cancer Genes Identified From GWAS Risk SNPs, Expression CluesPublished on Aug 09, 2019 In Brief This Week: Illumina, Invitae, MilliporeSigma, and MorePublished on Aug 09, 2019 People in the News: Priti Hegde, John Schoellerman, Randy Scott, Sean GeorgePublished on Aug 09, 2019Featured in Depth TGen-Led Team Prepares to Validate 'TARDIS' Blood-Based Cancer Monitoring MethodPublished on Aug 09, 2019 Thermal Profiling Identifies Functionally Significant Protein ModificationsPublished on Aug...
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Fair exchange: 10 things your agency should be paying forBy Mike RubinEMS agencies can spread goodwill by compensating providers for the extras, from skills enhancement to personal medical equipmentEnhancing wellbeing, engagement and patient care in EMS with weak tiesBy Russ MyersApproaching casual relationships intentionally in EMS has lasting implications for improving engagement and optimism in the EMS workforceDon't Be A Victim of Accidental Fentanyl ExposureLOW DERMA™ Technology, the first Protection...
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Malignant Solitary Fibrous Tumour of the Breast Mimicking a Benign TumorShow lessIsrael Barco, Clarisa González, Elena Vallejo, Antoni Pessarrodona, Nuria Giménez, Antonio García-FernándezFirst Published August 8, 2019 Research Article https://doi.org/10.1177/2632010X19868462Article information AbstractSolitary fibrous tumour (SFT) of the breast is exceedingly uncommon. Radiological assessment usually shows benign features. We report on a case of malignant SFT of the breast, while emphasizing the...
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Current opinions in nephrology and hypertension: kidney transplantation in patients with plasma cell dyscrasiasPurpose of review Plasma cell dyscrasias encompass a group of hematological disorders characterized by increased production of immunoglobulins by clonal B cells. Kidney involvement is common. Significant advances in the treatment of plasma cell dyscrasias have resulted in improved survival and may permit kidney transplantation in candidates previously denied transplantation. Treatments may...
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Cybersecurity Essentials for Nursing InformaticistsNo abstract availableThe Intersection of Mobile Health and Nursing Knowledge: Big Data ScienceNo abstract availableAlignment of American Association of Colleges of Nursing Graduate-Level Nursing Informatics Competencies With American Medical Informatics Association Health Informatics Core CompetenciesThis study yielded a map of the alignment of American Association of Colleges of Nursing Graduate-Level Nursing Informatics Competencies with American...
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Application of peripherally inserted central catheters in critically ill newborns experience from a neonatal intensive care unitPeripherally inserted central catheters (PICCs) can provide nutritional and medical support for very low birth weight or critically ill newborns. The aim of this study was to retrospectively analyze the use of PICCs in our clinic for critically ill newborns to evaluate the relationship between catheter related factors and the occurrence of complications. Retrospective analysis...
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Is oral rehydration in pediatric patients with gastroenteritis more effective than parenteral rehydration?No abstract availableA pain in the kneesNo abstract availableDon't pull the trigger: Subcutaneous injections of triamcinolone and lidocaine for postherpetic neuralgiaNo abstract availableDoes quadrupling the dose of inhaled glucocorticoids decrease severe exacerbations?No abstract availableIncreasing colorectal cancer screening ratesNo abstract availablePessary for preterm birthNo abstract availableDoes...
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The VE-PTP Inhibitor AKB-9778 Improves Antitumor Activity and Diminishes the Toxicity of Interleukin 2 (IL-2) AdministrationAdministration of interleukin (IL)-2 has led to a durable response in patients with advanced renal cancer and melanoma but is restricted for clinical application because of adverse effects, including the vascular leak syndrome (VLS). VLS is associated with increased circulating levels of the Tie2 antagonist ligand, angiopoietin 2, and decreased Tie2 receptor phosphorylation...
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Prenatal Diagnosis of Vasa Previa: Outpatient Versus Inpatient Management(Abstracted from Am J Perinatol 2019;36:422–427) Vasa previa is defined as fetal vessels that run through the fetal membranes, over or within 2-cm distance from the endocervical os and unprotected by the placenta or umbilical cord. Vasa previa is associated with a high fetal or neonatal mortality rate due to risk of fetal exsanguination resulting from the fetal vessels tearing when rupture of membranes occurs.Neurodevelopmental...
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Utility of Cyclin D1 in the Diagnostic Workup of Hematopoietic Neoplasms: What Can Cyclin D1 Do for Us?Cyclin D1, encoded by CCND1, promotes cell cycle progression from G1 to S phase. Its expression is induced by MAPK/ERK pathway as well as translocations/rearrangements involving CCND1 gene. The evaluation of cyclin D1 expression by immunohistochemistry plays an important role in the diagnostic workup of various hematopoietic diseases. In this review, we aimed to discuss the value of cyclin D1 immunostain...
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Patterns of Mutation Enrichment in Metastatic Triple-Negative Breast Cancer Show lessCésar H Saravia, Claudio Flores, Luis J Schwarz, Leny Bravo, Jenny Zavaleta, Jhajaira Araujo, Silvia Neciosup, Joseph A PintoFirst Published August 9, 2019 Research Article Triple-negative breast cancer (TNBC) is a heterogeneous disease with aggressive biology and complex tumor evolution. Our purpose was to identify enrichment patterns of genomic alterations in metastatic triple-negative breast cancer (mTNBC).Methods:Genomic...
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Ruhm alleine reicht nichtZusammenfassungObwohl Albert Neisser bereits als Student durch wissenschaftliche Leistungen aufgefallen war, blieb ihm eine Anstellung in der inneren Medizin versagt. Dies war zu dieser Zeit der strukturelle Alltag, da jüdischen Medizinern eine Karriere in den angesehenen Fächern Innere und Chirurgie verwehrt wurde. Obwohl er dann in der Dermatologie wegweisende Entdeckungen machte und so zur internationalen Berühmtheit wurde, ermöglichte erst der Wechsel nach Leipzig die...
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Brain Injury in Neonatal Hypoglycemia: A Hospital-Based Cohort StudyMei-Hong Gu, Fanny Amanda, Tian-Ming YuanFirst Published August 8, 2019 Research Article Neonatal hypoglycemia is more prevalent and can cause severe neurological sequelae. The objective of this study was to assess the patterns of neuroradiologic changes in neonatal hypoglycemia.Methods:A retrospective cohort study was conducted on 66 neonatal hypoglycemia patients, and the magnetic resonance imaging (MRI) and clinical records were...
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Costs and Benefits of Delaying Remediation on Ecological Resources at Contaminated SitesAbstractThe USA and other nations have massive industrial, radiologic, and chemical legacy wastes on numerous sites, for example from the Cold War and industrial activities. Most of these sites will require remediation (cleanup of contaminants). Prioritization is essential to determine the order of cleanup, leaving some tasks for a later time. This paper examines the potential costs and benefits of delaying remediation...
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Production of Galactose Oxidase Inside the Fusarium fujikuroi Species Complex and Recombinant Expression and Characterization of the Galactose Oxidase GaoA Protein from Fusarium subglutinansAbstractGalactose oxidase catalyzes a two-electron oxidation, mainly from the C6 hydroxyl group of d-galactose, with the concomitant reduction of water to hydrogen peroxide. This enzyme is secreted by Fusarium species and has several biotechnological applications. In this study, a screening of galactose oxidase...
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Studying Development in Williams Syndrome: Progress, Prospects, and ChallengesUsing Common Determinants of Out-of-Home Care to Profile Parents of Children and Adolescents with a Disability: an Exploratory StudyAbstractObjectivesThis study examined whether interrelationships between common psychosocial determinants of parental decisions to seek out-of-home care can identify parent profiles within a sample of parents of children and adolescents with a disability.MethodTwo hundred and sixteen parents...
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Digital Technology Adoption in Psychiatric Care: an Overview of the Contemporary Shift from Technology to OpportunityExamining the Impact of Geosocial Networking on the Sex Behaviors of Men Who Have Sex with MenAbstractMen who have sex with men (MSM) often use smartphone geosocial networking applications (GSN apps) to meet sex partners. Relative to non-GSN app users, MSM GSN app users have more sex partners. Research also reveals sexual-risk taking is associated with alcohol consumption and sexual...
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Presbyesophagus presented with chronic intermittent dysphagiaVZV-containing vaccines and hospitalization for herpes zoster: careful optimismThe repeatable battery for the assessment of the neuropsychological status (RBANS): a diagnostic validity study in Greek elderlyAbstractObjectiveThere is a broad need for a rapid and efficient neurocognitive battery to detect cognitive decline and differentiate MCI (mild cognitive impairment) and mild dementia from cognitively intact elders. The purpose of this...
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GM6 Attenuates Alzheimer's Disease Pathology in APP MiceThe name of author "William Swindell" missed the midle initial "R.". This should be written as "William R. Swindell" as corrected above.Correction to: Epigenetic regulation of neuronal immediate early genes is associated with decline in their expression and memory consolidation in scopolamine-induced amnesic miceThe original article inadvertently had a mistake in Fig. 3a and b. The authors regret to these errors.Correction to: Inhibitory Effects...
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Garrett on the Irrationality of Pure Time PreferencesAbstractIn "Experience and Time," Brian Garrett poses a challenge to friends of the rationality of pure time preferences. In this discussion note, we accept the challenge and provide two kinds of cases wherein some pure time preferences could be deemed rational.Hylomorphism: a Critical AnalysisAbstractIn this essay, I examine those versions of hylomorphism that attribute to form a very strong explicative role. According to them, form is both the...
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Nachsorge des muskelinvasiven Harnblasenkarzinoms nach kurativer TherapieZusammenfassungDie Nachsorge des muskelinvasiven Harnblasenkarzinoms gliedert sich in die onkologische und die funktionelle Nachsorge. Über 80 % aller Lokalrezidive und Fernmetastasen treten innerhalb der ersten 2 Jahre auf. Rezidive des verbleibenden Urothels treten auch mehrere Jahre nach radikaler Zystektomie auf. Die Urinzytologie und die Computertomographie (CT) des Thorax/Abdomens mit Urographiephase sind die Diagnostik...
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Tumor-induced escape mechanisms and their association with resistance to checkpoint inhibitor therapyAbstractImmunotherapy aims to activate the immune system to fight cancer in a very specific and targeted manner. Despite the success of different immunotherapeutic strategies, in particular antibodies directed against checkpoints as well as adoptive T-cell therapy, the response of patients is limited in different types of cancers. This attributes to escape of the tumor from immune surveillance and...
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Impact of pyridine-2-carboxaldehyde-derived aroylhydrazones on the copper-catalyzed oxidation of the M112A PrP 103–112 mutant fragmentAbstractMisfolded prion protein (PrPSc) is known for its role in fatal neurodegenerative conditions, such as Creutzfeldt–Jakob disease. PrP fragments and their mutants represent important tools in the investigation of the neurotoxic mechanisms and in the evaluation of new compounds that can interfere with the processes involved in neuronal death. Metal-catalyzed oxidation...
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Good Pharmacovigilance Practice in Paediatrics: An Overview of the Updated European Medicines Agency GuidelinesAnnual European Congress of RheumatologySafety and Tolerability of Adjunctive Brivaracetam in Pediatric Patients < 16 Years with Epilepsy: An Open-Label TrialAbstractObjectiveThis trial evaluated the short-term safety and tolerability, steady-state pharmacokinetics, and preliminary efficacy of brivaracetam oral solution in children aged 1 month to < 16 years with epilepsy.MethodsThis...
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Exercise Behaviors and Fatigue in Patients Receiving Immunotherapy for Advanced Melanoma: A Cross-Sectional Survey via Social MediaAmelia Hyatt, Allison Drosdowsky, Narelle Williams, Elizabeth Paton, Fiona Bennett, Hayley Andersen, Jared Mathai, and Donna MilneAugust 5, 2019Research ArticleThe Effect of Acupuncture in Breast Cancer–Related Lymphoedema (BCRL): A Systematic Review and Meta-AnalysisTsai-Ju Chien, Chia-Yu Liu, and Ching-Ju FangAugust 6, 2019
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An unusual cutaneous manifestation of Parvovirus B19 infection: papular‐purpuric gloves‐and‐socks...
An unusual cutaneous manifestation of Parvovirus B19 infection: papular‐purpuric gloves‐and‐socks syndrome and petechial bathing trunk eruptionA.S.M. Tidman, R. FatimaFirst Published: 10 August 2019CorrespondenceLong‐term outcomes of imiquimod‐treated lentigo maligna: Add on cryosurgery to induce inflammation and increase efficacy?G. Gaitanis, I.M. BassukasFirst Published: 06 August 2019CorrespondenceEruptive Melanocytic Naevi Provoked by Sunbed Use in the Setting of Systemic ImmunosuppressionC....
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The combined effect of tranilast 8% liposomal gel on the final cosmesis of acne scarring in patients concomitantly treated by isotretinoin: prospective, double‐blind, split‐face studyA. Weinstein, A. Koren, E. Sprecher, E. Zur, J. N. Mehrabi, O. ArtziVersion of Record online: 08 August 2019Viewpoints in dermatologyCorrespondenceComment on 'Bronchiolitis obliterans as a long‐term sequela of Stevens–Johnson syndrome and toxic epidermal necrolysis in children'A. AbdelmaksoudVersion of Record online:...
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NanomaterialsNanomaterials, Vol. 9, Pages 1152: The Synthesis, Structure, Morphology Characterizations and Evolution Mechanisms of Nanosized Titanium Carbides and Their Further ApplicationsNanomaterials, Vol. 9, Pages 1152: The Synthesis, Structure, Morphology Characterizations and Evolution Mechanisms of Nanosized Titanium Carbides and Their Further Applications Nanomaterials doi: 10.3390/nano9081152 Authors: Dong Qiu Li Shu Yang Jiang It is widely known that the special performances and extensive...
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International Journal of Environmental Research and Public HealthIJERPH, Vol. 16, Pages 2849: Metals in Occluded Water: A New Perspective for Pollution in Drinking Water Distribution SystemsIJERPH, Vol. 16, Pages 2849: Metals in Occluded Water: A New Perspective for Pollution in Drinking Water Distribution Systems International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16162849 Authors: Huiyan Tong Zhongyue Li Xingshuai Hu Weiping Xu Zhengkun Li Occluded water is water...
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Antibiotics, Vol. 8, Pages 117: Put a Bow on It: Knotted Antibiotics Take Center StageAntibiotics, Vol. 8, Pages 117: Put a Bow on It: Knotted Antibiotics Take Center Stage Antibiotics doi: 10.3390/antibiotics8030117 Authors: Stephanie Tan Gaelen Moore Justin Nodwell Ribosomally-synthesized and post-translationally modified peptides (RiPPs) are a large class of natural products produced across all domains of life. The lasso peptides, a subclass of RiPPs with a lasso-like structure, are structurally...
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