(Colorado State University) Colorado State University Professor Susan Bailey, who studies telomeres, or the protective 'caps' on the ends of chromosomes, found that Scott Kelly's telomeres in his white blood cells got longer while in space. Changes in telomere length could mean a person is at risk for accelerated aging or the diseases that come along with getting older. (Source: EurekAlert! - Cancer)
Thu Apr 11, 2019 06:00
(Cincinnati Children's Hospital Medical Center) Cell-by-cell genetic analyses of developing brain tissues in neonatal mice and laboratory models of brain cancer allowed scientists to discover a molecular driver of the highly aggressive, deadly, and treatment-resistant brain cancer, glioblastoma. Published in Cell Stem Cell, the findings present an opportunity to find out if new therapeutic approaches can stop glioblastoma at its earliest stages of initial formation or recurrence. (Source: EurekAlert!...
Thu Apr 11, 2019 06:00
(European Society for Medical Oncology) Maintenance immunotherapy fails to improve survival in extensive-stage small cell lung cancer (SCLC), according to late-breaking results from the CheckMate 451 study to be presented today at the European Lung Cancer Congress (ELCC) 2019. (Source: EurekAlert! - Cancer)
Thu Apr 11, 2019 06:00
(McMaster University) Bhatia's team spent more than six years delving down to the cellular level to examine what they say are previously overlooked cells that form on the edges of pluripotent stem cell colonies. Having characterized these cells, the team also observed them form at the earliest stages of pluripotent cell reprogramming from adult cells. (Source: EurekAlert! - Cancer)
Thu Apr 11, 2019 06:00
This study used data from a nationwide survey to estimate how many patients with cancer and cancer survivors use complementary and alternative medicines (CAMS) in addition to or instead of conventional therapies, and how many don't disclose that to their physicians. (Source: EurekAlert! - Cancer)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm...
Thu Apr 11, 2019 06:00
(American Society for Radiation Oncology) A new study finds wide state-by-state variations in Medicaid reimbursements to physicians who treat cancer patients with radiation therapies. These differences could compound existing disparities in access to health care in rural communities, which tend to have higher Medicaid coverage rates than metropolitan areas. The study is available for free access through April 24 in the International Journal of Radiation Oncology * Biology * Physics (Red Journal)....
Thu Apr 11, 2019 06:00
(Boston Children's Hospital) Most CAR T-cell therapies look for antigens specific to cancer cells. A new approach described in this week's PNAS instead targets the environment around the tumor, using unusually small antibodies made naturally by alpacas, camels and llamas. Using this approach in mouse models, investigators successfully curbed melanoma and colon cancer - solid tumors that currently can't be treated with CAR T-cell therapy. (Source: EurekAlert! - Cancer)
Thu Apr 11, 2019 06:00
(UT Southwestern Medical Center) A stunning one-third of people with a cancer diagnosis use complementary and alternative medicines such as meditation, yoga, acupuncture, herbal medicine, and supplements. (Source: EurekAlert! - Cancer)
Thu Apr 11, 2019 06:00
(Scripps Research Institute) Scientists at Scripps Research have identified a group of small molecules that prevent structural changes to proteins that are at the root of AL amyloidosis, a progressive and often fatal disease. The drug mechanism that the team identified is analogous to a different drug that also originated at Scripps Research: Tafamidis, which stabilizes the protein transthyretin to treat the most common systemic amyloid disease that affects the heart or other organs. (Source: EurekAlert!...
Thu Apr 11, 2019 06:00
(Source: Cancercompass News: Other Cancer)
Thu Apr 11, 2019 02:00
(Source: Cancercompass News: Other Cancer)
Thu Apr 11, 2019 02:00
(Source: Karmanos Cancer Institute)
Wed Apr 10, 2019 15:45
(Broad Institute of MIT and Harvard) Cancer cells adapt to potentially fatal mutations and other molecular malfunctions by adjusting one or more other genes' activity, in the process becoming dependent on those genes for their survival and growth. The resulting genetic dependencies may provide targets for developing new precision-guided drugs or other cancer treatment strategies.Reporting in Nature, researchers describe one such vulnerability shared by a large subset of colon, gastric, endometrial,...
Wed Apr 10, 2019 06:00
Already regretting hiring Cormac McCarthy to revise the script for Star Wars Ep. IX Boing BoingPreviously: Already regretting assigning J.G. Ballard to cover the Fyre Festival Already regretting assigning the new MacBook Pro review to Borges Already ...
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The sialoglycoprotein podocalyxin is absent in normal pancreas but is overexpressed in pancreatic cancer and is associated with poor clinical outcome. Here we investigate the role of podocalyxin in migration and metastasis of pancreatic adenocarcinomas using SW1990 and Pa03c as cell models. Although ezrin is regarded as a cytoplasmic binding partner of podocalyxin that regulates actin polymerization via Rac1 or RhoA, we did not detect podocalyxin-ezrin association in pancreatic cancer cells. Moreover,...
Thu Apr 11, 2019 17:16
Publication date: August 2019Source: Materials Science and Engineering: C, Volume 101Author(s): Hira Choudhury, Manisha Pandey, Tan Hui Yin, Taasjir Kaur, Gan Wei Jia, S.Q. Lawrence Tan, How Weijie, Eric Koh Sze Yang, Chin Guan Keat, Subrat Kumar Bhattamishra, Prashant Kesharwani, Shadab Md, Nagasekhara Molugulu, Mallikarjuna Rao Pichika, Bapi GorainAbstractMultidrug resistance (MDR) is one of the key barriers in chemotherapy, leading to the generation of insensitive cancer cells towards administered...
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Publication date: August 2019Source: Materials Science and Engineering: C, Volume 101Author(s): Xueyun Chen, Ming Fan, Huaping Tan, Bowen Ren, Guoliang Yuan, Yang Jia, Jianliang Li, Dangsheng Xiong, Xiaodong Xing, Xiaohong Niu, Xiaohong HuAbstractIn order to broaden the abilities of injectable hydrogel scaffolds, a self-healing chitosan/alginate hydrogel encapsulated with magnetic gelatin microspheres (MGMs) was prepared for anti-cancer drug delivery and soft tissue engineering. The hydrogel was...
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