Antibodies, Vol. 8, Pages 27: Single-Domain Antibodies as Therapeutic and Imaging Agents for the Treatment of CNS Diseases Antibodies doi: 10.3390/antib8020027 Authors: Kasandra Bélanger Umar Iqbal Jamshid Tanha Roger MacKenzie Maria Moreno Danica Stanimirovic Antibodies have become one of the most successful therapeutics for a number of oncology and inflammatory diseases. So far, central nervous system (CNS) indications have missed out on the antibody revolution, while...
Fri Apr 05, 2019 03:00
Antibodies, Vol. 8, Pages 26: VHH-Photosensitizer Conjugates for Targeted Photodynamic Therapy of Met-Overexpressing Tumor Cells Antibodies doi: 10.3390/antib8020026 Authors: Raimond Heukers Vida Mashayekhi Mercedes Ramirez-Escudero Hans de Haard Theo C. Verrips Paul. M.P. van Bergen en Henegouwen Sabrina Oliveira Photodynamic therapy (PDT) is an approach that kills (cancer) cells by the local production of toxic reactive oxygen species upon the local illumination of...
Thu Apr 04, 2019 03:00
Antioxidants, Vol. 8, Pages 93: Effect of the Phosphodiesterase 5 Inhibitor Sildenafil on Ischemia-Reperfusion-Induced Muscle Mitochondrial Dysfunction and Oxidative Stress Antioxidants doi: 10.3390/antiox8040093 Authors: Liliane Tetsi Anne-Laure Charles Isabelle Georg Fabienne Goupilleau Anne Lejay Samy Talha Myriam Maumy-Bertrand Claire Lugnier Bernard Geny Lower-limb ischemia-reperfusion (IR) is frequent and associated with significant morbidity and mortality....
Sun Apr 07, 2019 03:00
Antioxidants, Vol. 8, Pages 92: Polyphenolic Composition of Rosa canina, Rosa sempervivens and Pyrocantha coccinea Extracts and Assessment of Their Antioxidant Activity in Human Endothelial Cells Antioxidants doi: 10.3390/antiox8040092 Authors: Kerasioti Apostolou Kafantaris Chronis Kokka Dimitriadou Tzanetou Priftis Koulocheri Haroutounian Kouretas Stagos The aim of the present study was the investigation of the antioxidant activity of plant...
Sat Apr 06, 2019 03:00
Antioxidants, Vol. 8, Pages 91: Juglone in Oxidative Stress and Cell Signaling Antioxidants doi: 10.3390/antiox8040091 Authors: Ahmad Suzuki Juglone (5-hydroxyl-1,4-naphthoquinone) is a phenolic compound found in walnuts. Because of the antioxidant capacities of phenolic compounds, juglone may serve to combat oxidative stress, thereby protecting against the development of various diseases and aging processes. However, being a quinone molecule, juglone could also act as a redox cycling...
Fri Apr 05, 2019 03:00
Antioxidants, Vol. 8, Pages 90: Antioxidant Activities of Alkyl Substituted Pyrazine Derivatives of Chalcones—In Vitro and In Silico Study Antioxidants doi: 10.3390/antiox8040090 Authors: Stepanić Matijašić Horvat Verbanac Kučerová-Chlupáčová Saso Žarković Chalcones are polyphenolic secondary metabolites of plants, many of which have antioxidant activity. Herein, a set of 26 synthetic chalcone derivatives with alkyl substituted pyrazine heterocycle A and four...
Fri Apr 05, 2019 03:00
Antioxidants, Vol. 8, Pages 89: Antioxidants and Male Fertility: from Molecular Studies to Clinical Evidence Antioxidants doi: 10.3390/antiox8040089 Authors: Martin-Hidalgo Bragado Batista Oliveira Alves Spermatozoa are physiologically exposed to reactive oxygen species (ROS) that play a pivotal role on several sperm functions through activation of different intracellular mechanisms involved in physiological functions such as sperm capacitation associated-events. However,...
Fri Apr 05, 2019 03:00
Antioxidants, Vol. 8, Pages 88: Effects of Extra Virgin Olive Oil and Apples Enriched-Dark Chocolate on Endothelial Progenitor Cells in Patients with Cardiovascular Risk Factors: A Randomized Cross-Over Trial Antioxidants doi: 10.3390/antiox8040088 Authors: Felice Francini Domenici Cifelli Belardinelli Sebastiani Cantini Di Stefano Background: Endothelial dysfunction has been associated to cardiovascular outcomes in patients with cardiovascular risk factors....
Thu Apr 04, 2019 03:00
Antioxidants, Vol. 8, Pages 87: Luteolin 7-Sulfate Attenuates Melanin Synthesis through Inhibition of CREB- and MITF-Mediated Tyrosinase Expression Antioxidants doi: 10.3390/antiox8040087 Authors: Seok Won Lee Jae Heon Kim Hyerim Song Jin Kyung Seok Seong Su Hong Yong Chool Boo Antioxidants with antimelanogenic activity are potentially useful for the attenuation of skin hyperpigmentation disorders. In a previous study, luteolin 7-sulfate isolated from Phyllospadix iwatensis...
Thu Apr 04, 2019 03:00
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