Selection Pressures of Vancomycin Powder Use in Spine Surgery: A Meta-analysis

Surgical site infection (SSI) is a serious and costly complication of spine surgery. Many surgeons apply vancomycin powder to the surgical wound to prevent SSIs. While multiple studies have reported reduced rates of SSI, others have suggested that widespread use of intra-wound vancomycin may increase the incidence of vancomycin-resistant, gram-negative, or polymicrobial spinal infections.

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