Σάββατο 12 Ιανουαρίου 2019

HIIT Improves Left Ventricular Exercise Response in Adults with Type 2 Diabetes

Type 2 diabetes is associated with reduced left ventricular reserve. It is unclear whether exercise training improves left ventricular function in people with type 2 diabetes. PURPOSE To determine whether three months of high intensity interval training (HIIT) improves left ventricular function during exercise in adults with type 2 diabetes. METHODS Participants performed a V[Combining Dot Above]O2peak test and received a DXA scan and total blood volume measurement at baseline. Left ventricular end diastolic volume (LVEDV), end systolic volume (LVESV) and stroke volume (LVSV) were then measured at rest and during low- and moderate-intensity semi-recumbent exercise in adults with type 2 diabetes before and after three-months of HIIT (N = 11) or no training (control) (N = 5). The effects of HIIT were determined using ANOVA with repeated measures. RESULTS HIIT increased V[Combining Dot Above]O2peak by approximately 15% (P 0.05). HIIT augmented the reduction in LVESV from rest to moderate intensity exercise (P 0.05). CONCLUSIONS HIIT training increased the LVSV response to exercise in adults with type 2 diabetes. These data suggest HIIT can improve LV filling and emptying during exercise and reverse early cardiac consequences of type 2 diabetes. Corresponding Author: James Christopher Baldi, Ph.D., Department of Medicine, 9th Floor, Dunedin Hospital, Great King Street, Dunedin 9016, New Zealand. Chris.baldi@otago.ac.nz This study was funded by Anderson's Trust and Healthcare Otago Charitable Trust obtained by J.C. Baldi. The authors have no conflict of interest to declare. The results of the present study do not constitute endorsement by the American College of Sports Medicine. The results of the study are presented clearly, honestly, and without fabrication, falsification, or inappropriate data manipulation. Accepted for Publication: 14 December 2018 © 2019 American College of Sports Medicine

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