The risk for complications associated with joint and soft-tissue injections in patients taking direct oral anticoagulants (DOACs) is not fully understood. In this retrospective evaluation of 445 inpatients in a rehabilitation hospital who received corticosteroid injections, complications were compared in patients on DOACs with those who were not. After a review of all injections, no adverse events of significant bleeding (intra-articular or extra-articular) were observed. These findings suggest no substantial increase in adverse events associated with the use of DOACs when performing joint and soft-tissue injection procedures in inpatient rehabilitation setting. Correspondence to David M. Lipson, MD, FRCPC, Providence Healthcare, 3276 St Clair Avenue, East Toronto, ON, Canada M1L 1W1 Tel: +1 416 285 3619; fax: +1 416 285 3764; e-mail: dlipson@providence.on.ca Received September 26, 2018 Accepted November 11, 2018 Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.
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