Πέμπτη 29 Νοεμβρίου 2018

EEG analysis in anti-NMDA receptor encephalitis: description of typical patterns

Anti-N-methyl D-aspartate receptor encephalitis (anti-NMDARE) is the most frequent human autoimmune encephalitis and is primarily directed against the NR1 subunit of the NMDAR (Dalmau et al., 2008). Clinical symptoms are initially marked by psychiatric manifestations, impaired cognition and seizures followed by movement disorders, loss of consciousness, and dysautonomia (Dalmau et al., 2011, 2008; Irani et al., 2010; Titulaer et al., 2013) The association of one of these symptoms and anti-NMDAR IgG antibodies detection made a definite diagnosis (Graus et al., 2016).

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