Early Functional Outcomes for Pediatric Patients Diagnosed with Anti-NMDA Receptor Encephalitis during Inpatient Rehabilitation

Objective The aims of the current study were to characterize the demographic and clinical presentation of pediatric patients diagnosed with anti-NMDA receptor encephalitis who require inpatient rehabilitation, to examine early functional outcomes, and to investigate predictors of early recovery. Design A retrospective chart review was conducted for 27 pediatric patients diagnosed with anti-NMDA receptor encephalitis who received intensive inpatient neurorehabilitation. Results On average, patients were 10.6 years of age (range 2-18) at the time of symptom onset. Average time to treatment from symptom onset was 27.2 days (range 5-91). Patients displayed significant improvements between admission and discharge WeeFIM DFQ scores across patients (p<.01 mean weefim total dfq score at admission was and discharge younger age onset seizures number of treatments received associated with worse functional outcomes discharge. time to initiate treatment not found be early outcomes. conclusion pediatric patients diagnosed anti-nmda receptor encephalitis displayed significant gains during inpatient rehabilitation despite persistent deficits suggesting the need for ongoing monitoring intervention. correspondence: robyn a. howarth phd children healthcare atlanta department neuropsychology meridian mark road suite ga phone: fax: email: robyn.howarth author disclosures: none funding: no funding copyright wolters kluwer health inc. all rights reserved.>

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