It is time to remove the stigma from glial scars: re: Lentivirus-mediated silencing of the CTGF gene suppresses the formation of glial scar tissue in a rat model of spinal cord injury

For over two decades, glial scars were stigmatized for creating a non-permissive environment for axonal regrowth and hampering functional recovery after spinal cord injury (SCI). Since the identification of myelin-derived inhibitors [1,2], much effort has been dedicated to the development of therapies designed to inhibit glial scar formation or change the molecular environment within the scar (chondroitin sulfate proteoglycan barrier) [3,4].

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