Intrinsic Network Reactivity Differentiates Levels of Consciousness in Comatose Patients

Coma and other disorders of consciousness (DOC) is associated with profound reductions in wakefulness and awareness (Bruno et al., 2011; Giacino et al., 2014; Laureys, 2005). Linking these behavioral markers with specific injury attributes remains a persistent clinical challenge (McGee et al., 2016). Electroencephalographic recordings offer the potential to help to disassociate underlying causes of DOC by revealing systematic electrophysiological correlates of injury and behavior (Sitt et al., 2014; Sebastiano et al., 2015).

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