CAN anterior cervical fusion procedures prevent the progression of the natural course of Hirayama disease? An ambispective cohort analysis

Hirayama disease (HD) is a special neurological disease that is characterised by muscular weakness and atrophy in the upper extremities without sensory involvement (Hirayama, 2008; Zhou et al., 2010; Hassan and Sahni, 2013). The main hypotheses for the aetiology of HD implicates chronic ischemia of cervical motor neurons caused by neck flexion (Hirayama et al., 1987; Imai et al., 1999; Zheng et al., 2016). Furthermore, some previous studies suggest that the disease progression of HD may stop at 2-4 years after the onset (Tan, 1985; Tashiro et al., 2006; Huang et al., 2008).

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