Τρίτη 17 Ιουλίου 2018

Conservation of mRNA quality control factor Ski7 and its diversification through changes in alternative splicing and gene duplication [Genetics]

Eukaryotes maintain fidelity of gene expression by preferential degradation of aberrant mRNAs that arise by errors in RNA processing reactions. In Saccharomyces cerevisiae, Ski7 plays an important role in this mRNA quality control by mediating mRNA degradation by the RNA exosome. Ski7 was initially thought to be restricted to Saccharomyces...

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