Phantom somatosensory evoked potentials following selective intraneural electrical stimulation in two amputees

Following a limb amputation and consequent truncation of nerves, some of the nerve fibers originally directed to the lost part of the body suffer from retrograde Wallerian degeneration. However, a significant part of them survive in the residual portion of the nerve (Navarro et al., 2007). Due to the development of neural interfaces for the peripheral nervous system, i.e. intraneural multichannel electrodes (Navarro et al., 2005), it was recently demonstrated that it is possible to induct meaningful sensations (Dhillon et al., 2005) in the phantom hand of amputees by stimulating the surviving fibers through these interfaces.

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