Intraoperative Hippocampal Electrocorticography Frequently Captures Electrographic Seizures and Correlates with Hippocampal Pathology

In patients with pharmacoresistant temporal lobe epilepsy (TLE), the epileptogenic zone commonly involves the medial temporal lobe structures including the hippocampus. Removal of the hippocampus by resecting the medial temporal lobe either selectively or along with the temporal neocortex provides lasting seizure freedom (Datta et al., 2009; Kumar et al., 2013; Mittal et al., 2005; Olivier, 2000; Tanriverdi et al., 2008; Wiebe et al., 2001; Wieser et al., 2003; Wieser and Yasargil, 1982; Yasargil et al., 2010).

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